Results 161 to 170 of about 175,055 (304)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Addition of metformin for non-small cell lung cancer patients receiving antineoplastic agents. [PDF]

Front Pharmacol, 2023
Wang Y, Hu Y, Wang T, Che G, Li L.
europepmc   +1 more source

195 Nurses and antineoplastic agents: factors influencing exposure risk [PDF]

, 2016
David M. DeJoy, Todd D. Smith, Henok G. Woldu, Aimee Dyal   +3 more
openalex   +1 more source

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

Advanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park, Jeehee Lee, Young Yong Kim, Sanghee Lee, Yongju Kim   +4 more
wiley   +1 more source

First use of antineoplastic agents in women with breast cancer in the state of Rio de Janeiro, Brazil. [PDF]

Front Pharmacol, 2023
Dos Santos RLB, Osorio-de-Castro CGS, Sobreira-da-Silva MJ, Pepe VLE.   +3 more
europepmc   +1 more source

CPC-125 Satisfaction Survey with Pharmaceutical Care in Ambulatory Cancer Patients on Treatment with Oral Antineoplastic Agents [PDF]

, 2013
MA Fernández de Palencia, Laura Naranjo, MJ Sánchez Garre, MS Díaz Carrasco, Cristina Roig, J Mateo Carmona, A De la Rubia Nieto   +6 more
openalex   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents. [PDF]

Molecules, 2022
Mancini I, Vigna J, Sighel D, Defant A.
europepmc   +1 more source

Antineoplastic Agents Associated With Thyroid Dysfunction [PDF]

, 2011

openalex   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source