Assessing the risk of tumor lysis syndrome associated with the use of antineoplastic agents: a real-world pharmacovigilance study based on the FDA Adverse Event Reporting System database [PDF]
Background: The use of antineoplastic agents is one of the important triggers of tumor lysis syndrome (TLS), but there is still a lack of comprehensive understanding of antineoplastic agents that may trigger TLS and the TLS risk differences between ...
Dongxuan Li+6 more
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Background Medical gloves are an important piece of personal protective equipment that prevents exposure to antineoplastic agents. The permeability of medical gloves to antineoplastic agents is a crucial factor in the appropriate selection of gloves ...
Toyohito Oriyama+7 more
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Prediction of the permeability of antineoplastic agents through nitrile medical gloves by zone classification based on their physicochemical properties [PDF]
Background Permeability of antineoplastic agents through medical gloves is an important factor that must be considered for the appropriate selection of gloves.
Toyohito Oriyama+6 more
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External contamination of commercial containers by antineoplastic agents: a literature review. [PDF]
The aim of this study was to review the literature regarding the external contamination of commercial vials by antineoplastic drugs. A PubMed and CINAHL searches from 1 January 1990 to 1 May 2018 was performed with the terms: « antineoplastic agents », «
Hilliquin D, Tanguay C, Bussières JF.
europepmc +2 more sources
Mucocutaneous Reactions to Antineoplastic Agents [PDF]
Mucocutaneous reaction patterns in patients receiving cancer therapy are not only variable, but in many instances identical patterns are produced by different pathologic mechanisms. For example, patients with leukemia or lymphoma may present with nodular skin lesions that may represent malignant infiltration, septic emboli, vasculitis, or a drug ...
R. M. Adrian+2 more
openalex +4 more sources
Data on drug–drug interactions (DDI) of antineoplastic drugs with anticoagulants is scarce. We aim to evaluate factors associated with DDI of antineoplastic and supportive care drugs with anticoagulants resulting in modification of pharmacokinetics of ...
Érique José F. Peixoto de Miranda MD, PhD+6 more
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Extravasation of antineoplastic agents: prevention and treatments
The extravasation of antineoplastic agents is an unwanted and distressing situation that can easily occur. It may cause severe and irreversible local injuries.
Rita Boschi, Elena Rostagno
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Renal toxicity of antineoplastic agents
Most of the drugs currently used in the treatment of cancer are highly cytotoxic and possess relatively low therapeutic selectivity. Given the major role of the kidney in the excretion of these drugs or their metabolites, it is perhaps surprising that clinically significant nephrotoxicity occurs with a limited number of drugs.
Richard F. Borch, Thomas J. Montine
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Cytotoxic Activity of Antineoplastic Agents on Fertility: A Systematic Review [PDF]
Objective: To analyze the long-term effects of antineoplastic treatments on patient fertility. Selection of Studies: The studies were selected through the New PubMed, Scielo and Lilacs databases along with references used for the creation of the present
Gabriel Acácio de Moura+1 more
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Design and Synthesis of Organic Molecules as Antineoplastic Agents [PDF]
The fight against cancer is one of the most challenging tasks currently for lots of researchers in many fields, such as pharmaceuticals, medicine, and chemicals [...]
Carla Boga, Gabriele Micheletti
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