Results 61 to 70 of about 8,664 (277)

New Mediators and Growth Factors Affecting Pterium Growth

Acta Medica Alanya, 2017
Pterjium is an ocular surface disorder and is a pathologic result of corneal invasion of the fibro-vascular proliferation of the bulb conjunctiva in the region corresponding to the lid space.
Leyla Eryi̇ği̇t Eroğul
doaj   +1 more source

Evaluation and Validation of clinical 4.23 T sodium MRI in animals and human: Application of oblique multi-slice spin-echo pulse sequence [PDF]

, 2009
Objective: Application of high-field 4.23 T MRI clinical imager was demonstrated for sodium-magnetic resonance imaging (MRI) data acquisition. Primary hypothesis: Sodium [Na] in brain is MR visible. Secondary hypothesis was, if, application of multislice
Jose Katz, Rakesh Sharma
core   +1 more source

Optimizing drug therapy in patients with advanced dementia: A patient-centered approach [PDF]

, 2014
Background: Advanced dementia is a prevalent health problem in geriatric patients. These patients usually suffer from several chronic diseases, frequently leading to an end-of-life situation lasting months or years, generating complex and often ...
American Geriatrics Society Beers Criteria Update Expert P., Beer, Boyd, Coleman, Crome, Cruz-Jentoft, Gallagher, Garfinkel, Garfinkel, Gnjidic, Gómez-Batiste, Hall, Hartholt, Holmes, Le Couteur, Lopez Mongil, Maltoni, Marcum, Martin, Mitchell, Mitchell, O’Mahony, Qaseem, Reuben, Schiff, Thomas, World Health Organization National Institute on Aging   +26 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Mecanismos de cardiotoxicidad: antineoplásicos, anti-inflamatorios no esteroideos, antipsicóticos, cocaetileno y simpaticomiméticos Mechanisms of cardiotoxicity: antineoplastics, nonsteroidal anti-inflammatory drugs, antipsychotics, cocaethylene and sympathomimetics

Revista Colombiana de Cardiología, 2011
La interacción constante del organismo humano con diferentes sustancias, que incluso en muchas ocasiones se consideran inofensivas, tiene un alto impacto sobre todos los sistemas, siendo el cardiovascular uno de los más afectados.
Lukas Salazar, Ana Cristina Palacio, Javier R Rodríguez   +2 more
doaj  

Acute coronary syndrome due to midazolam use: Kounis syndrome during a transurethral prostatectomy

Türk Kardiyoloji Derneği Arşivi, 2015
Developments in the drugs industry are leading to more rare drug side effects being encountered in clinical practice. Of these side effects, allergic reactions and hypersensitivity are seen in the usage of a large group of drugs such as antibiotics ...
Ahmet Hakan Ateş, Selim Kul
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Socio-demographic and disease related characteristics associated with unplanned emergency department visits by cancer patients: a retrospective cohort study

BMC Health Services Research, 2019
Background Emergency department (ED) presentations made by patients having cancer treatment are associated with worse outcomes. This study aimed to explore the socio-demographic and disease related characteristics associated with ED presentation ...
Polly H. Dufton, Allison Drosdowsky, Marie F. Gerdtz, Mei Krishnasamy   +3 more
doaj   +1 more source

Total Knee Periprosthetic Joint Infection in the Setting of Hematologic Malignancy: Considerations for Management

Arthroplasty Today, 2020
Patients with malignancy are often profoundly immunocompromised due to chemotherapy, placing them at potential increased risk for periprosthetic joint infection (PJI). However, there is little information regarding PJI management in these patients.
G. Barnes Bloom, BSCE, Simon C. Mears, MD, PhD, Paul K. Edwards, MD, C. Lowry Barnes, MD, Jeffrey B. Stambough, MD   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source