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Antineutrophil cytoplasm antibodies and vasculitis [PDF]
Systemic vasculitis is a rare condition and diagnosis is often difficult. Any organ system can be affected and patients can present with an insidiously progressive illness, a remitting/relapsing pattern, or acute multisystem failure. The early institution of aggressive and potentially toxic immunosuppression may be necessary to minimise permanent organ
M C, Nash, M J, Dillon
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Background Antineutrophil cytoplasmic antibody-associated vasculitis is dominated by inflammatory occlusion of small vessels, causing tissue ischemia in various organs.
Maassoumeh Akhlaghi Kalahroodi +4 more
doaj +1 more source
Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis [PDF]
Brett Elicker +2 more
exaly +2 more sources
Antineutrophil cytoplasmic antibodies: appropriate use and interpretation [PDF]
It was with much interest that we read the letter of Novikov et al 1 on testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with ANCA-associated vasculitides (AAV) and other diseases. In their letter, the authors (1) share their experience with direct testing for proteinase-3 (PR3) ANCA and myeloperoxidase (MPO) ANCA and (2) raise ...
Damoiseaux, Jan +4 more
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The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Anticorpos contra o citoplasma de neutrófilos Antineutrophil cytoplasmic antibodies
A descoberta do marcador sorológico denominado anticorpo anticitoplasma de neutrófilos revolucionou o diagnóstico e o seguimento das vasculites pulmonares, especialmente da granulomatose de Wegener. Seu padrão pode ser citoplasmático e perinuclear.
Ari Stiel Radu, Mauricio Levi
doaj +1 more source
Case Report of Atypical Course of MPO-ANCA Associated Vasculitis
The classic form of vasculitis associated with antineutrophil cytoplasmic antibodies is characterized by progressive severe course, multiple lesions of internal organs and a general treatment strategy.
O.R. Boiarchuk, S.I. Smiian
doaj +1 more source
Antineutrophil cytoplasmic antibodies (ANCA)
Antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker for ANCA-associated systemic vasculitis. Using indirect immunofluorescence on ethanol-fixed neutrophils, two major fluoroscopic patterns can be recognised: a diffuse cytoplasmic staining (C-ANCA), and a perinuclear/nuclear staining (P-ANCA).
Radice, A, SINICO, RENATO ALBERTO
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Antineutrophil cytoplasmic antibodies: reporting and diagnostic strategies [PDF]
It was with great interest that we read the correspondence of Mahler and Fritzler1 on our recent European Vasculitis Study Group (EUVAS) study describing the performance of immunoassays for antineutrophil cytoplasmic antibodies (ANCA) in patients with ANCA-associated vasculitides (AAV).2 In their letter, Mahler and Fritzler raise some interesting ...
Damoiseaux, Jan +4 more
openaire +3 more sources
Antineutrophil Cytoplasmic Antibodies and Infection
(1993). Antineutrophil Cytoplasmic Antibodies and Infection. Autoimmunity: Vol. 15, No. 1, pp. 81-83.
J M, Durand +7 more
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