Results 131 to 140 of about 45,444 (286)

Evaluating plasma antinuclear autoantibody profile as a prognostic biomarker in lymphoma

BMC Cancer
Background Research on the antinuclear antibodies (ANA) profile across different pathological subtypes of lymphoma was limited. Our study aimed to assess ANA profile and investigate its potential prognostic value in lymphoma.
Cuiling Zheng, Ruyun Gao, Yanrong Wang, Xiaohong Han   +3 more
doaj   +1 more source

Epstein‐Barr virus as a driver of lupus: Rethinking triggers in autoimmunity

Rheumatology &Autoimmunity, EarlyView.
Jiekai Tan, Fanlei Hu, Chuanhui Xu
wiley   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Clinical Significance of Anti‐Atezolizumab Antibodies in Patients With Unresectable Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab

Hepatology Research, EarlyView.
ABSTRACT Aim Systemic therapy is required for unresectable hepatocellular carcinoma (HCC). Atezolizumab plus bevacizumab (ATZ/BEV) is the recommended first‐line treatment for HCC; however, the development of anti‐drug antibodies (ADAs) against ATZ may impair its therapeutic efficacy. Although ADAs have been reported in other cancers treated with immune
Keishi Ouchi, Jun Inoue, Masashi Ninomiya, Mio Tsuruoka, Kosuke Sato, Kotaro Doi, Kengo Watanabe, Tomoya Sasazaki, Atsushi Masamune   +8 more
wiley   +1 more source

Association between Antinuclear Antibodies Patterns and Immunological Markers with Systemic Lupus Erythematosus in Iraqi Female Patients

Background: Systemic lupus erythematosus is a condition where the immune system attacks various tissues and organs, affecting commonly women between the ages of 15 to 44. It is caused by genetics or environmental factors.
Humaish, Haider Hafudh, Zeki, Ali Yahya, Al-Hafid, Ali Hussein   +2 more
core   +1 more source

Use of cultured epithelial cells, including keratinocytes, for the detection of antinuclear antibodies.

, 1987
The use of cultured human epithelial cells as a substrate for the detection of antinuclear antibodies (ANAs) improves the sensitivity of detection above the standard substrates used.
Leigh, I, Zhu, T, Wojnarowska, F, Burge, S, Bhogal, B   +4 more
core   +1 more source

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

Hepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda, Shuichiro Umetsu, Eitaro Hiejima, Mitsuyoshi Suzuki, Itaru Iwama, Takeshi Kimura, Sonoko Kondo, Ayano Inui, Hiroki Kondou, Tatsuya Okamoto, Takashi Ito, Hiroyuki Shirahase, Kazushi Izawa, Takahiro Yasumi, Takeshi Kuwada, Masahiro Shiokawa, Hiroshi Seno, Junko Takita   +17 more
wiley   +1 more source

Review Article - Antinuclear Antibodies: Clinical Applications

, 2003
One of the common serological hallmarks of autoimmune disorders is the presence of various autoantibodies in the sera of patients affected by these disorders.
Wanchu A
core  

CH50 as a Clinically Useful Biomarker of Disease Activity and Antihistamine Resistance in Chronic Spontaneous Urticaria: An Observational Ambispective Single‐Center Study

International Journal of Dermatology, EarlyView.
Personalized CSU care guided by CH50. ABSTRACT Background Chronic spontaneous urticaria (CSU) is frequently refractory to guideline‐based therapy, highlighting the need for predictive biomarkers. Dysregulation of the complement system has been implicated in CSU severity, but global complement activity has not been systematically evaluated.
Nidia Planella‐Fontanillas, Emilio Berna‐Rico, David Pesqué, Evelyn Andrades, Silvia Sánchez, Paloma Torres‐Bosó, Ramon Gimeno, Fernando Gallardo, Ramon M. Pujol, Ana M. Giménez‐Arnau   +9 more
wiley   +1 more source

ANTI DEOXYRIBONUCLEIC ACID AND ANTINUCLEAR ANTIGEN ANTIBODIES IN GRAVES’ DISEASE

, 2005
Graves’ disease is an autoimmune disorder characterized by presence of antibodies directed against thyroid stimulating hormone (TSH) receptor or nearby region.
H. Mostafavi
core