Results 141 to 150 of about 57,235 (275)

Branch retinal artery occlusion due to patent foramen ovale in a teenager

Experimental Physiology, EarlyView.
Abstract This report demonstrates the diagnostic evaluation and clinical management of a 16‐year‐old girl who developed branch retinal artery occlusion secondary to patent foramen ovale. The goal is to increase awareness of this rare presentation in adolescents among clinicians, with a summary of the important clinical features, multimodal imaging ...
Jie Zu, Fang Fan, Jiayao Wang, Jianmin Wang, Zhiyang Jia   +4 more
wiley   +1 more source

Monoclonal Antibodies Accessing the Cytosol of Living Cells and Binding to Polo‐Like Kinase 1 Interdomain Linker Affect Mitotic Behavior

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
Monoclonal antibodies targeting the interdomain region of polo‐like kinase 1 (PLK1) were delivered into living HeLa cells by electroporation to directly modulate mitotic progression. This intracellular antibody approach provides a new tool to probe PLK1 function and highlights the potential of antibodies to regulate key mitotic regulators inside cells.
Clément Steyer, Jean-Christophe Amé, Mariel Donzeau, Karie Shen, Manuela Chiper, Guy Zuber   +5 more
wiley   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Lingual Dyskinesia as the Presenting Feature of Acquired Demyelinating Syndrome: A Case Report and Review of Differential Diagnoses

Journal of Paediatrics and Child Health, EarlyView.
Briana Davis, Ahmed Kaki, Eppie M. Yiu, Emma Macdonald‐Laurs   +3 more
wiley   +1 more source

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, Volume 78, Issue 5, Page 662-669, May 2026.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source

Antinuclear Antibodies Predict Treatment Escalation and Biologic Switching in Rheumatoid Arthritis. [PDF]

Diagnostics (Basel)
Akar ZA, Yıldırım D, Çiftçi M, Işık Sula Z, Karaman S, Çevik R, Karakoç M, Em S, Batmaz İ, Oktayoğlu P, Çağlayan M.   +10 more
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Immunoprecipitation-mass spectrometry reveals known and novel (NatC, <i>BCS1L</i>) antinuclear antibodies in rheumatoid arthritis. [PDF]

RMD Open
De Leeuw J, Michiels B, Derua R, Vulsteke JB, Dillaerts D, Cockx M, Verschueren P, Bossuyt X.   +7 more
europepmc   +1 more source

Acute Intermittent Porphyria Triggered by COVID‐19 Mimicking Guillain–Barré Syndrome: A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Acute intermittent porphyria (AIP) is a rare heme biosynthesis disorder in which the accumulation of neurotoxic porphyrin precursors precipitates neurovisceral attacks. Intercurrent infections, including coronavirus disease 2019 (COVID‐19), may trigger or exacerbate AIP and complicate diagnosis, as clinical manifestations can resemble those of
Payman Sadeghi, Masood Ghahvechi Akbari, Seyed Abbas Hassani, Hosein Alimadadi, Morteza Heidari, Vahid Ziaee   +5 more
wiley   +1 more source

Change in Antinuclear Antibodies After Lung Transplantation in Patients with Systemic Sclerosis. [PDF]

J Clin Med
Barreales-Rodríguez V, Guillen-Del-Castillo A, Berastegui C, López-Meseguer M, Monforte V, Saez-Gimenez B, Villar A, Ojanguren I, Codina-Clavaguera C, Fernández-Luque A, Sanz-Martínez MT, Viñas-Giménez L, Perurena-Prieto J, Triginer-Gil L, Alcalá-González L, Bravo C, Simeón Aznar CP.   +16 more
europepmc   +1 more source