Results 1 to 10 of about 1,337,423 (351)

Prevalence of pulmonary arterial hypertension in patients with connective tissue diseases: a systematic review of the literature [PDF]

open access: yesClinical Rheumatology, 2013
Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease. Understanding of PAH prevalence remains limited, but PAH has been reported as a frequent complication in connective tissue diseases.
Jack Mardekian   +4 more
exaly   +2 more sources

Nailfold capillaroscopy in rheumatic connective tissue diseases [PDF]

open access: yesRheumatology
Capillaroscopy is a non-invasive examination used for imaging of capillary vessels of the papillary layer of the finger nailfold. It allows the detection of microcirculation disorders in systemic connective tissue diseases.
Ewa Wielosz, Natalia Siedlecka
doaj   +2 more sources

Cold intolerance and associated factors: a population study

open access: yesScientific Reports, 2022
Cold intolerance has been defined as a set of symptoms including pain, tingling, numbness, chills, stiffness, weakness, swelling or skin color changes on exposure to cold. Cold intolerance may have a profound effect on health-related quality of life.
Alireza Khabbazi   +8 more
doaj   +1 more source

Combinations of scleroderma hallmark autoantibodies associate with distinct clinical phenotypes

open access: yesScientific Reports, 2022
Systemic sclerosis (SSc) is characterized by the presence of SSc-specific or SSc-associated antibodies (SSc-Abs): anti-topoisomerase I (ATA), anti-centromere (ACA), anti-RNA polymerase III (ARA), anti-U3RNP (U3RNP), anti-U1RNP (U1RNP), anti-PmScl (PmScl),
Kristina E. N. Clark   +6 more
doaj   +1 more source

Safety of liver function monitoring every 3 months in patients treated with low dose methotrexate [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2014
Introduction: The objective of this study was to evaluate the safety of liver transaminases monitoring every 12 weeks in patients with inflammatory connective tissue disorders who aretreated with methotrexate (MTX). Methods: In a retrospective study, the
Alireza Khabbazi   +11 more
doaj   +1 more source

The prevalence and significance of anti-PM/Scl antibodies in systemic sclerosis

open access: yesAnnals of Agricultural and Environmental Medicine, 2021
Introduction Anti-PM/Scl (a-PM/Scl) antibodies are found in different systemic autoimmune diseases such as polymyositis, dermatomyositis, systemic sclerosis (SSc) and overlap syndromes. According to literature, they are detected in approx.
Ewa Wielosz   +2 more
doaj   +1 more source

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis

open access: yesArthritis Research & Therapy, 2021
Background The TβRII∆k-fib transgenic (TG) mouse model of scleroderma replicates key fibrotic and vasculopathic complications of systemic sclerosis through fibroblast-directed upregulation of TGFβ signalling.
Emma Derrett-Smith   +10 more
doaj   +1 more source

Hypoparathyroidism as one of the initial presentations of systemic lupus erythematosus

open access: yesClinical Case Reports, 2022
Systemic lupus erythematosus (SLE) is an autoimmune disease and may be associated with many autoimmune conditions. Hypoparathyroidism is a rare disease. The leading cause of hypoparathyroidism is postsurgical hypoparathyroidism.
Leyla Gadakchi   +4 more
doaj   +1 more source

Axonal sensory‐motor polyneuropathy in ankylosing spondylitis: A case report

open access: yesClinical Case Reports, 2023
Key Clinical Message In ankylosing spondylitis cases, axonal‐type sensory‐motor polyneuropathy is a rare manifestation and should be considered an underlying etiology in patients with unexplained neuropathy.
Amirreza Khalaji   +3 more
doaj   +1 more source

Effect of Nigella sativa oil extracts on inflammatory and oxidative stress markers in Behcet’s disease: A randomized, double-blind, placebo-controlled clinical trial [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2020
Objective: Behcet's disease (BD) is a chronic inflammatory disorder characterized by recurrent oral and genital aphthous ulcers, uveitis and skin lesions. Oxidative stress and inflammation have important role in the pathogenesis of BD.
Shahrzad Amizadeh   +7 more
doaj   +1 more source

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