Results 21 to 30 of about 1,337,423 (351)

Disorders of the Aorta and Aortic Valve in Connective Tissue Diseases

Current Cardiology Reports, 2020
Purpose of Review The incidence of aortic valve disease in inherited connective tissue disorders is well documented; however, recent studies have only begun to unravel the pathology behind this association. In this review, we aim to describe the etiology,
B. Grygiel-Górniak, M. Oduah, Abdulbaril Olagunju, Michal Klokner   +3 more
semanticscholar   +1 more source

Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis

Frontiers in Immunology, 2022
BackgroundRecent evidence has indicated that alterations in energy metabolism play a critical role in the pathogenesis of fibrotic diseases. Studies have suggested that ‘metabolic reprogramming’ involving the glycolysis and oxidative phosphorylation ...
Isabella Gomes Cantanhede, Isabella Gomes Cantanhede, Huan Liu, Huan Liu, Huan Liu, Vestaen Balbuena Rodriguez, Xu Shiwen, Voo H. Ong, Christopher P. Denton, Markella Ponticos, Guo Xiong, José Luiz Lima-Filho, David Abraham, Jeries Abu-Hanna, Jan-Willem Taanman   +14 more
doaj   +1 more source

Interstitial Lung Disease and Other Pulmonary Manifestations in Connective Tissue Diseases

Mayo Clinic proceedings, 2019
Lung involvement in connective tissue diseases is associated with substantial morbidity and mortality, most commonly in the form of interstitial lung disease, and can occur in any of these disorders. Patterns of interstitial lung disease in patients with
I. Mira-Avendano, A. Abril, C. Burger, P. Dellaripa, A. Fischer, M. Gotway, Augustine S. Lee, Joyce S. Lee, E. Matteson, E. Yi, J. Ryu   +10 more
semanticscholar   +1 more source

Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)

Annals of the Rheumatic Diseases, 2020
Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and connective tissue disease (CTD-ILD), such as rheumatoid arthritis-ILD and systemic ...
P. Spagnolo, O. Distler, C. Ryerson, A. Tzouvelekis, Joyce S. Lee, F. Bonella, Demosthenes Bouros, A. Hoffmann-Vold, B. Crestani, E. Matteson   +9 more
semanticscholar   +1 more source

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials [PDF]

, 2013
Rationale Clinical trial design in interstitial lung diseases (ILDs) has been hampered by lack of consensus on appropriate outcome measures for reliably assessing treatment response.
Antoniou, K, Baughman, RP, Brown, KK, Castelino, FV, Christmann, RB, Christopher-Stine, L, Collard, HR, Cottin, V, Danoff, S, Dellaripa, PF, Denton, CP, Distler, O, Fischer, A, Flaherty, KR, Frankel, S, Highland, KB, Hummers, L, Huscher, D, Khanna, D, Kim, DS, Kowal-Bielecka, OM, LeSage, D, Lynch, DA, Matteson, EL, Merkel, PA, Miller, FW, Mittoo, S, Oddis, CV, Phillips, K, Pittrow, D, Proudman, SM, Richeldi, L, Ryu, JH, Saketkoo, LA, Sandorfi, N, Sarver, C, Seibold, JR, Shah, AA, Strand, V, Swigris, J, Wells, AU   +40 more
core   +1 more source

Host reaction in paratenic fish hosts against 3rd stage larvae of Anguillicola crassus [PDF]

, 1996
Many fish species of Lake Balaton (Hungary) serve as paratenic hosts for the 3rd stage larvae of the eel parasite Anguillicola crassus. The incidence oi different phases of the host reaction varies with paratenic fish host but its nature is basically the
Molnár, Kálmán, Pazooki, Jamileh, Székely, Csaba   +2 more
core   +1 more source

Carotid Artery Tortuosity Is Associated with Connective Tissue Diseases

American Journal of Neuroradiology, 2019
BACKGROUND AND PURPOSE: There is a general assumption in the cerebrovascular literature that there is an association between carotid artery tortuosity and connective tissues disease; however, this has not been firmly established.
John P. Welby, S. Kim, C. M. Carr, V. Lehman, C. Rydberg, J. Wald, P. Luetmer, Deena M. Nasr, W. Brinjikji   +8 more
semanticscholar   +1 more source

Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis

Cardiovascular Ultrasound, 2018
Background The study presents a prospective follow-up assessment of cardiovascular (CV) risk parameters in patients with rheumatoid arthritis (RA) in comparison with control subjects. Methods The study group consisted of 41 RA patients.
Bożena Targońska-Stępniak, Mariusz Piotrowski, Robert Zwolak, Anna Drelich-Zbroja, Maria Majdan   +4 more
doaj   +1 more source

Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. [PDF]

, 2017
Implanted biomaterials and biomedical devices generally induce foreign body reaction and end up with encapsulation by a dense avascular fibrous layer enriched in extracellular matrix.
Chu, Julia, Gong, Xiaohua, Huang, Wen-Chin, Li, Song, Li, Ye, Qiu, Xuefeng, Wang, Aijun, Wang, Dong, Wu, Fan, Xu, Kang   +9 more
core   +2 more sources

Microangiopathic antiphospholipid syndrome (MAPS) in the course of undifferentiated connective tissue disease

Journal of Medical Science, 2014
Introduction. The microangiopathic antiphospholipid syndrome (MAPS) is a subset of APS comprising those patients presenting with thrombotic microangiopathy and demonstrable antiphospholipid antibodies. Renal involvement occurs frequently in the course of
Bożena Targońska-Stępniak, Ewa Wielosz, Maria Majdan   +2 more
doaj   +1 more source