Results 161 to 170 of about 1,482,126 (355)

Systemic lupus erythematosus and nephritis: severe relapse with disappearance of antinuclear antibodies. [PDF]

, 1980
Nicholas J. White, C. G. Winearls, J G Ledingham   +2 more
openalex   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source

Immunology and Disease of Connective Tissue [PDF]

, 1977
Since immune responses play a major role in the development of connective tissue diseases, it is not surprising that a number of laboratory studies reflect these responses. Prior to the 1940s when rheumatoid and LE factors became widely known, one relied
Irby, Robert
core   +1 more source

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Afimetoran, a Toll‐Like Receptor 7 and 8 Inhibitor, in Patients With Cutaneous Lupus Erythematosus: A Phase 1b Randomized, Double‐Blind, Placebo‐Controlled Study

ACR Open Rheumatology, Volume 7, Issue 7, July 2025.
Objective There is an unmet need for safe and effective oral treatments for cutaneous lupus erythematosus (CLE). Afimetoran is an investigational, first‐in‐class, orally bioavailable, selective small molecule inhibitor of Toll‐like receptors (TLRs) 7 and 8.
Fareeda Hosein, Stanislav Ignatenko, Kristina D. Chadwick, Lin Zhu, Frédéric Baribaud, Jasmine Saini, Thanh Bach, Urvi Aras, WanYing Zhang, Hazem Karabeber, Michelle Dawes, Melanie Harrison, Leonidas N. Carayannopoulos, Gopal Krishna   +13 more
wiley   +1 more source

Hydralazine antinuclear antibodies and the lupus syndrome. [PDF]

, 1982
Lawrence E. Ramsay, J H Silas, S Freestone   +2 more
openalex   +1 more source

Is COVID-19 severity unrelated to antinuclear antibodies? [PDF]

Transpl Immunol, 2023
Vahabi M, Mirsharif ES, Ghazanfari T.
europepmc   +1 more source

COVID19‐Related Onset and Relapses of Juvenile Systemic Lupus Erythematosus‐Like Disease

Journal of Paediatrics and Child Health, EarlyView.
Chiara Cannata, Francesca Tirelli, Alessandra Meneghel, Francesco Zulian   +3 more
wiley   +1 more source

Antinuclear antibodies and the diagnosis of systemic lupus erythematosus in patients with acute intermittent porphyria. [PDF]

, 1990
S. A. Allard, P. Charles, Ariane L. Herrick, K E McColl, J T Scott   +4 more
openalex   +1 more source

Absence of Functional Autoantibodies Targeting Angiotensin II Receptor Type 1 and Endothelin‐1 Type A Receptor in Circulation and Purified IgG From Patients With Systemic Sclerosis

Arthritis &Rheumatology, Volume 77, Issue 7, Page 901-913, July 2025.
Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen, Eva M. Hoekstra, E. W. Nivine Levarht, Ilana B. Kotliar, Thomas P. Sakmar, René E. M. Toes, Jeska K. de Vries‐Bouwstra, Laura H. Heitman, Cynthia M. Fehres   +8 more
wiley   +1 more source

Assessing serum anti-nuclear antibodies HEp-2 patterns in synucleinopathies

Immunity & Ageing
This study investigates the presence of antinuclear antibodies (ANA) in three primary synucleinopathies – Parkinson’s disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), compared to healthy controls.
Jonas Folke, Marie Skougaard, Trine-Line Korsholm, Anne-Line Strange Laursen, Lisette Salvesen, Anne-Mette Hejl, Sara Bech, Annemette Løkkegaard, Tomasz Brudek, Sisse Bolm Ditlev, Susana Aznar   +10 more
doaj   +1 more source