Results 21 to 30 of about 42,297 (231)

Could Antinuclear Antibody Positivity Be a Factor Affecting Treatment Response in Immune Thrombocytopenia Patients on Eltrombopag?

Turkish Journal of Hematology, 2022
Objective: Eltrombopag remains a prominent option in the treatment of steroid-dependent or steroid-refractory immune thrombocytopenia (ITP) patients. Unfortunately, not all patients respond to eltrombopag.
Mehmet Baysal, Volkan Baş, Elif Ümit, Hakkı Onur Kırkızlar, Ahmet Muzaffer Demir   +4 more
doaj   +1 more source

Intracellular and circulating neuronal antinuclear antibodies in human epilepsy

Neurobiology of Disease, 2013
There are overwhelming data supporting the inflammatory origin of some epilepsies (e.g., Rasmussen's encephalitis and limbic encephalitis). Inflammatory epilepsies with an autoimmune component are characterized by autoantibodies against membrane-bound ...
Philip H. Iffland, II, Juliana Carvalho-Tavares, Abhishek Trigunaite, Shumei Man, Peter Rasmussen, Andreas Alexopoulos, Chaitali Ghosh, Trine N. Jørgensen, Damir Janigro   +8 more
doaj   +1 more source

Antinuclear Antibodies in Patients with Psoriatic Arthritis Treated or Not with Biologics. [PDF]

PLoS ONE, 2015
With the emergence of biotherapies, accurate diagnosis in early arthritis is needed. At this time, there is no biological marker of psoriatic arthritis.To test whether antinuclear antibodies (ANA) can be used as a diagnostic tool in psoriatic arthritis ...
Florent Silvy, Daniel Bertin, Nathalie Bardin, Isabelle Auger, Marie-Caroline Guzian, Jean-Pierre Mattei, Sandrine Guis, Jean Roudier, Nathalie Balandraud   +8 more
doaj   +1 more source

Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited

Diagnostic Pathology, 2009
It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their detection or confirmation.
Minz Ranjana, Bhatia Alka, Kumar Yashwant   +2 more
doaj   +1 more source

Immunology markers that can be predictive for the diagnosis of juvenile idiopathic arthritis

Journal of Laboratory Medicine, 2020
This study aimed to investigate the implications of antinuclear antibodies (ANAs) in juvenile idiopathic arthritis (JIA), the association with uveitis and the favorable evolution of the disease.
Sur Lucia M., Silaghi Ciprian, Colceriu Marius C., Sur Daniel G., Aldea Cornel, Sur Genel, Floca Emanuela, Tataru Alexandru, Lupan Iulia, Samasca Gabriel   +9 more
doaj   +1 more source

Clinical diagnoses associated with a positive antinuclear antibody test in patients with and without autoimmune disease

BMC Rheumatology, 2023
Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will develop an autoimmune disease, and ...
Jacy T. Zanussi, Juan Zhao, Wei-Qi Wei, Gul Karakoc, Cecilia P. Chung, QiPing Feng, Nancy J. Olsen, C. Michael Stein, Vivian K. Kawai   +8 more
doaj   +1 more source

Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy

Przegląd Dermatologiczny, 2018
Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal, Marta Sar-Pomian, Joanna Czuwara, Lidia Rudnicka   +3 more
doaj   +1 more source

Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant

Case Reports in Transplantation, 2022
Background. Catastrophic antiphospholipid syndrome (CAPS) is an autoimmune thrombogenic disorder of small and large vessels caused by autoantibodies against phospholipids and phospholipid-binding proteins.
R. Okeke, J. Lok, R. Wells, M. Wycoff, A. Engelhardt, J. Bettag, C. O’Leary, T. Hallcox, M. Nazzal   +8 more
doaj   +1 more source

Autoantibody profiles and their association with blood eosinophils in asthma and COPD

Allergology International, 2017
Background: Autoimmune involvement in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been proposed, and autoantibodies are a hallmark of autoimmunity.
Koji Tamai, Harukazu Yoshimatsu, Toshiharu Saito, Hirofumi Matsuoka, Nobuhiko Okada, Yasuko Koma, Akiko Otsuka, Nao Oda, Sayaka Inoue, Sachie Kume, Yujiro Suzuki   +10 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source