CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]
Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya +58 more
core +3 more sources
Nonsystemic vasculitic neuropathy
A 21-year-old female born of nonconsanguineous marriage presented with gradually progressive quadriplegia for 3 years. Weakness was distal more than proximal, with wasting. She also had moderate pain in extremities.
Shalesh Rohatgi +2 more
doaj +1 more source
Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]
ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core +2 more sources
Antinuclear Antibodies: A demographic profile from a Tertiary Healthcare Centre of Delhi
Background: Anti-nuclear autoantibodies (ANA), have explicitly been linked to immune complex-mediated autoimmune diseases. Detection and quantitation of autoantibodies are therefore crucial in the diagnosis and treatment.
Krishna Sarkar +3 more
doaj +1 more source
A 50 year old with a rapid neuropsychiatric deterioration and choreaform movements [PDF]
A 50-year-old man presented acutely to the hospital with behavioural disturbance, choreiform movements and profound nihilistic delusions. He reported recent drug and alcohol abuse, and also apparent involvement in several recent criminal activities, for ...
Campbell, Stewart +3 more
core +1 more source
Intracellular and circulating neuronal antinuclear antibodies in human epilepsy
There are overwhelming data supporting the inflammatory origin of some epilepsies (e.g., Rasmussen's encephalitis and limbic encephalitis). Inflammatory epilepsies with an autoimmune component are characterized by autoantibodies against membrane-bound ...
Philip H. Iffland, II +8 more
doaj +1 more source
Antineutrophil cytoplasmic antibodies (ANCAs) are associated with small vessel vasculitis but their prevalence is not rare in other immune diseases.
Joana Eugénio Santos +6 more
doaj +2 more sources
Objective: Eltrombopag remains a prominent option in the treatment of steroid-dependent or steroid-refractory immune thrombocytopenia (ITP) patients. Unfortunately, not all patients respond to eltrombopag.
Mehmet Baysal +4 more
doaj +1 more source
Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M +3 more
core +1 more source
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources

