It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their detection or confirmation.
Minz Ranjana +2 more
doaj +1 more source
Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant
Background. Catastrophic antiphospholipid syndrome (CAPS) is an autoimmune thrombogenic disorder of small and large vessels caused by autoantibodies against phospholipids and phospholipid-binding proteins.
R. Okeke +8 more
doaj +1 more source
Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource Limited Setting in Tanzania: A Case Report, Clinical Discussion and Brief Review of Existing Literature. [PDF]
Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor ...
A Cénac +27 more
core +3 more sources
Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy
Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal +3 more
doaj +1 more source
Immunology markers that can be predictive for the diagnosis of juvenile idiopathic arthritis
This study aimed to investigate the implications of antinuclear antibodies (ANAs) in juvenile idiopathic arthritis (JIA), the association with uveitis and the favorable evolution of the disease.
Sur Lucia M. +9 more
doaj +1 more source
Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will develop an autoimmune disease, and ...
Jacy T. Zanussi +8 more
doaj +1 more source
Case of severe hypertension and nephrotic range proteinuria [PDF]
No abstract ...
Bursztyn, Michael +4 more
core +1 more source
The presence of abnormal levels of autoantibodies to intracellular antigens is a hallmark of systemic connective tissue disease. The indirect immunofluorescence assay is the most commonly used routine test for the detection of antinuclear antibodies.
openaire +2 more sources
Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. [PDF]
BackgroundFirst reported in 1955, Cronkhite-Canada syndrome (CCS), a rare syndrome characterized by ectodermal abnormalities and inflammatory changes of the gastrointestinal tract mucosa, has been associated with a poor prognosis and life-threatening ...
Hibi, Toshifumi +8 more
core +1 more source
Autoantibody profiles and their association with blood eosinophils in asthma and COPD
Background: Autoimmune involvement in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been proposed, and autoantibodies are a hallmark of autoimmunity.
Koji Tamai +10 more
doaj +1 more source

