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Clinics in Laboratory Medicine, 2019
The presence of antinuclear antibodies (ANAs), which include autoantibodies to extractable nuclear antigens (ENAs), in the sera of patients with connective tissue diseases provides useful immunologic and pathophysiologic insight into the nature of their disease.
Mandakolathur R. Murali, Morris Ling
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The presence of antinuclear antibodies (ANAs), which include autoantibodies to extractable nuclear antigens (ENAs), in the sera of patients with connective tissue diseases provides useful immunologic and pathophysiologic insight into the nature of their disease.
Mandakolathur R. Murali, Morris Ling
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[Application of Antinuclear Antibody and Antinuclear Antibody Spectrum in Lymphoma Treatment].
Zhongguo shi yan xue ye xue za zhi, 2020To investigate the significance of antinuclear antibody and antinuclear antibody spectrum in the stage and prognosis of lymphoma patients.79 cases of lymphoma (lymphoma group) treated in the Second Affiliated Hospital of Fujian Medical University and 50 cases of healthy people (control group) were selected. Antinuclear antibodies (ANA) were detected by
Chun-Mei Fan, Mei-E Wang
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Antinuclear antibodies and recurrent miscarriage: Systematic review and meta‐analysis
American Journal of Reproductive Immunology, 2019Studies have investigated the relationship between antinuclear antibodies (ANA) and recurrent miscarriage (RM). The objective of this paper is to evaluate the presence of ANA as a risk factor for spontaneous abortion in patients with RM.
M. Cavalcante+4 more
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COMMENTS ON ANTINUCLEAR ANTIBODIES
Archives of Dermatology, 1968To the Editor.— Drs. Rowell and Beck in their article in the September 1967 issue of theArchives 1 once again stated that the speckle-inducing antinuclear antibody is as frequent in systemic lupus erythematosus (SLE) as it is in scleroderma. We originally reported that "speckled" fluorescence was almost exclusively confined to scleroderma in our ...
Thomas R. Neblett+2 more
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Antinuclear antibodies in dermatology
Seminars in Cutaneous Medicine and Surgery, 2001Antinuclear antibodies are used in the diagnosis and evaluation of patients with connective tissue diseases. The study of antinuclear antibodies has also fundamentally expanded our understanding of nuclear anatomy and function. This article reviews the clinically relevant antinuclear antibodies and their disease associations.
Jennifer H. Do+2 more
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Clinics in Laboratory Medicine, 2002
The ANA test is an excellent screening test for patients with SLE and a few other connective tissue diseases. The LE cell preparation is an assay that is subjective and costly. Because of the presence of a superior screening test (the ANA) and superior specific auto-antibody tests, the author recommends that the use of LE cell preparations be ...
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The ANA test is an excellent screening test for patients with SLE and a few other connective tissue diseases. The LE cell preparation is an assay that is subjective and costly. Because of the presence of a superior screening test (the ANA) and superior specific auto-antibody tests, the author recommends that the use of LE cell preparations be ...
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The Clinical Significance of Antinuclear Antibodies
Postgraduate Medicine, 1973A number of different types of antinuclear antibodies have been characterized, and their clinical significance is beginning to become clear. The anti-DNA type correlates closely with renal injury and severity of clinical disease in systemic lupus erythematosus. Antiribonucleoprotein appears to be related to mixed connective tissue disease.
Eng M. Tan+2 more
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Absorption of serum antinuclear antibodies
Clinical Immunology and Immunopathology, 1979Abstract The absorption out of antinuclear antibody (ANA) from sera of highly ANA-positive C57BL/6 mice was obtained by different cellular and noncellular factors. A single injection of DNA, liver nuclei, thymocytes, or repeated injections of a soluble material produced by normal mouse splenocytes with (SIRS+) or without (SIRS−) previous stimulation ...
David Geltner, Alpha Peled
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Antinuclear Antibodies in Multiple Sclerosis
Archives of Neurology, 1982Low levels of antinuclear antibodies (ANAs) were found by indirect immunofluorescence in the serum of patients with multiple sclerosis (MS). Antibodies were found in 22 (81%) of 27 patients with MS and four (20%) of 20 healthy control subjects, with human epithelial (HEp-2) cells as substrate. Antinuclear antibody titers ranged from 8 to 32 in patients
Robert B. Zurier+3 more
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Antinuclear antibodies in psychiatric patients
Acta Psychiatrica Scandinavica, 1994To investigate whether unrecognized systemic lupus erythematosus (SLE) might occur more frequently among psychiatric patients than expected on clinical examination, sera of 100 patients from a psychiatric hospital were tested for the presence of antibodies against nuclear antigens (ANA) and antibodies against DNA.
Ferdinand C. Breedveld+2 more
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