A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim +5 more
wiley +1 more source
Antinuclear antibody targets in autoimmune hepatitis and drug-induced liver injury: Diagnostic relevance of nucleosome antibodies. [PDF]
Kolev M +8 more
europepmc +1 more source
A 61‐year‐old man with asthma, peripheral eosinophilia, and characteristic peripheral opacities was suspected of having chronic eosinophilic pneumonia (CEP), despite bronchoalveolar lavage showing marked neutrophil predominance and only 6% eosinophils.
Yang‐Tai Lin +5 more
wiley +1 more source
A risk stratification model identifies a high-risk subgroup for connective tissue disease among dermatology patients with positive antinuclear antibody testing: A retrospective cohort study. [PDF]
Lee CH, Choi Y.
europepmc +1 more source
Personalized CSU care guided by CH50. ABSTRACT Background Chronic spontaneous urticaria (CSU) is frequently refractory to guideline‐based therapy, highlighting the need for predictive biomarkers. Dysregulation of the complement system has been implicated in CSU severity, but global complement activity has not been systematically evaluated.
Nidia Planella‐Fontanillas +9 more
wiley +1 more source
Study on the dynamic changes in antinuclear antibody spectrum in SARS-CoV-2 infection: a retrospective analysis. [PDF]
Zheng J +8 more
europepmc +1 more source
Incidence of cutaneous lupus erythematosus and systemic progression: A Nationwide study in Korea
This nationwide study reports a cutaneous lupus erythematosus (CLE) incidence of 3.98/100,000 person‐years. CLE was associated with an increased risk of actinic keratosis and skin cancer. Progression to SLE clustered within 5 years after CLE diagnosis, with a 5‐year cumulative incidence of 11.4%, supporting a risk‐stratified follow‐up approach during ...
Seon Young Song +3 more
wiley +1 more source
Genetic Analysis of Asymptomatic Antinuclear Antibody Production. [PDF]
Hocaoǧlu M +2 more
europepmc +1 more source
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley +1 more source
Effect of hydroxychloroquine on pregnancy outcomes in women with unexplained recurrent pregnancy loss complicated with antinuclear antibody positivity: a multicentre prospective cohort study protocol. [PDF]
Ma B +9 more
europepmc +1 more source

