Results 191 to 200 of about 552,216 (306)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability. [PDF]

Front Immunol
Yin B, Juan C, Zhang R, Yang S, Wang H, Liu Y, Song S, Yan Z, Yi Y, Zhao Z, Huang Z, Lin S.   +11 more
europepmc   +1 more source

Assessment of Cystamine's Radioprotective/Antioxidant Ability under High-Dose-Rate Irradiation: A Monte Carlo Multi-Track Chemistry Simulation Study. [PDF]

Antioxidants (Basel), 2023
Penabeï S, Meesungnoen J, Jay-Gerin JP.
europepmc   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

The effect of Japanese eel as a main ingredient on hair condition, antioxidant ability, apparent total tract digestibility and body weight gain in cat food. [PDF]

Front Vet Sci
Yuan Y, Zhu L, Cai X, Mao H, Wang T, Tao S, Bao J, Liu C, Feng J.   +8 more
europepmc   +1 more source

High Antioxidant Ability Confer Resistance to Atrazine in Commelina communis L. [PDF]

Plants (Basel), 2021
Yang J, Yu H, Cui H, Chen J, Li X.
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Effect of Ultra-High Pressure on the Extraction of the Free, Esterified, and Bound Phenolics from <i>Dendrobium fimbriatum</i> Hook: Chemical Constituents and Antioxidant Ability. [PDF]

Molecules
Su Q, Hu J, Cui H, Zheng F, Liu Y, Wang Z, Cheng G.   +6 more
europepmc   +1 more source

Dietary supplementation with nano-composite of copper and carbon on growth performance, immunity, and antioxidant ability of yellow-feathered broilers. [PDF]

J Anim Sci, 2023
Liu J, Lin S, Wu S, Lin Q, Fan Z, Wang C, Ye D, Guo P.   +7 more
europepmc   +1 more source