Results 41 to 50 of about 644,422 (294)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Nanoparticles with Antioxidant Activity

open access: yesAntioxidants
Oxidative stress is commonly defined as an imbalance between reactive oxygen species (ROS) production and an organism’s ability to neutralize them via antioxidant defense mechanisms, leading to damage to biomolecules, including lipids, proteins, and DNA [...]
Regina G. Daré   +1 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A REVIEW OF MARINE NATURAL PRODUCTS AS POTENTIAL SOURCE OF ANTIOXIDANTS

open access: yesBiotropia: The Southeast Asian Journal of Tropical Biology
Article Highlights - Marine Natural Products have been the most favorable source of bioactive compounds for drug discovery research. - Many biologically active chemicals with antioxidant properties can be found in the marine environment.
Rhesa Hinampas, Angelo Mark Walag
doaj   +1 more source

Bivariate Correlation Analysis of the Chemometric Profiles of Chinese Wild Salvia miltiorrhiza Based on UPLC-Qqq-MS and Antioxidant Activities

open access: yesMolecules, 2018
To better understand the mechanisms underlying the pharmacological actions of Salvia miltiorrhiza, correlation between the chemical profiles and in vitro antioxidant activities in 50 batches of wild S. miltiorrhiza samples was analyzed.
Xiaodan Zhang   +8 more
doaj   +1 more source

Characterization, optimization of preparation process of an Inonotus obliquus polysaccharide-Zinc (II) complex and its antioxidant activities

open access: yesBiotechnology & Biotechnological Equipment, 2021
Zinc deficiency in human body has gradually become a major challenge to public health in modern society. In our previous work, a novel polysaccharide from Inonotus obliquus IP3a was successfully isolated and purified.
Ding Xiao   +6 more
doaj   +1 more source

Elucidating Flavonoid and Antioxidant Activity in Edible and Medicinal Herbs Woodwardia japonica (L.f.) Sm. Based on HPLC-ESI-TOF-MS and Artificial Neural Network Model: Response to Climatic Factors

open access: yesMolecules, 2023
Woodwardia japonica is a kind of great potential edible and medicinal fern. In a previous study, it was found that flavonoid and antioxidant activity of W. japonica from different sites were different. However, the cause of the differences has still been
Xin Wang   +5 more
doaj   +1 more source

Antioxidant and antihypertensive activities of rice bran peptides [PDF]

open access: yes, 2011
Protein isolates and peptide fractions from food sources (cereal grains), have been shown to exert bioactive properties including antiobesity, anticancer, antiangiogenic, etc.
Hettiarachchy, Navam S.   +2 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Antioxidant activities of Barringtonia racemosa leaves

open access: yesFood Research, 2017
Proximate analysis of Barringtonia racemosa (putat) leaves was carried out and total phenolic content (TPC) was measured using total phenolic assay, also known as the Folin Ciocalteu (FC) assay.
Nurul Syafizan, R., Rabeta, M.S.
doaj   +1 more source

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