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Microbial antioxidant defense enzymes
Microbial Pathogenesis, 2017Free radicals are often described as chemical compounds characterized by unpaired electrons in their outer orbital rendering them highly reactive species. In mammalians, studies on free radicals were focused on reactive oxygen species (ROS) or reactive nitrogen species (RNS) due to their relative importance in physiological as well as in pathological ...
Staerck, Cindy +8 more
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Antioxidant Enzymes and Apoptosis
Drug Metabolism Reviews, 2004The role of antioxidant enzymes can be interpreted in terms of fine tuning of the concentration of reactive oxygen species which are required in the redox regulation of the cell cycle and of programmed cell death. This review summarizes findings from papers published in the last few years which deal with the relation between apoptosis and the two ...
Regine, Kahl +3 more
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Antioxidant Enzymes and Diabetic Retinopathy
Annals of the New York Academy of Sciences, 2007Abstract: The aim of this study was to discuss the serum copper (Cu), zinc (Zn), nitric oxide (NO), glutathione (GSH), advanced oxidation protein products (AOPP) levels, and superoxide dismutase (SOD) activities with diabetic retinopathy severity.
Guersel, E. +4 more
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Antioxidant Enzyme Mimics with Synergism
Mini-Reviews in Medicinal Chemistry, 2010The antioxidant enzymes, such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase contribute dominatingly to enhance cellular antioxidant defense against oxidative stress. They act cooperatively to scavenge reactive oxygen species, and not one of them can singlehandedly clear all forms of reactive oxygen species. On
Fei, Yan +5 more
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Antioxidant enzymes and human diseases
Clinical Biochemistry, 1999To describe the importance of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase working together in human cells against toxic reactive oxygen species, their relationship with several pathophysiologic processes and their possible therapeutic implications.Reactive oxygen species (ROS) are involved in the cell growth ...
J M, Matés +2 more
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Antioxidant Enzymes in Human Tears
Journal of Ocular Pharmacology and Therapeutics, 1991Minimally stimulated tear samples collected from human subjects were assayed for the major antioxidant enzymes: superoxide dismutase, catalase and glutathione peroxidase. No catalase or glutathione peroxidase activity was detected. However, human tear film does contain the CuZn superoxide dismutase (103 +/- 32 ng/mg soluble protein), which is ...
R K, Crouch +3 more
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Journal of Sports Sciences, 2005
Free radical production increases during exercise and oxidative damage occurs in several tissues. We examined the effects of three different exercise tests on the pattern of change of erythrocyte enzyme antioxidant activities. The tests were a short maximal exercise test, a submaximal prolonged exercise test and a cycling stage during competition.
P, Tauler +7 more
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Free radical production increases during exercise and oxidative damage occurs in several tissues. We examined the effects of three different exercise tests on the pattern of change of erythrocyte enzyme antioxidant activities. The tests were a short maximal exercise test, a submaximal prolonged exercise test and a cycling stage during competition.
P, Tauler +7 more
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Regulation of Antioxidant Enzymes
The Journal of Nutrition, 1992Free radicals generated by a partial reduction of O2 pose a serious hazard to tissues and vital organs, especially membrane lipids, connective tissues, and the nucleic acids of cells. For protection, enzymes have evolved that specifically attack O2-, hydrogen, and organic peroxides, and repair any damage incurred to DNA.
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Antioxidant enzymes in oral verrucous carcinoma
Journal of Oral Pathology & Medicine, 2016BackgroundVerrucous carcinoma is a non‐metastasizing variant of welldifferentiated squamous cell carcinoma, which has been associated with reactive oxygen species generated by betel quid chewing. Salivary antioxidant systems have been suggested to play a protective role in reducing the oxidative damage.
Ting-Ying, Fu +3 more
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Caloric restriction, aging, and antioxidant enzymes
Mutation Research/DNAging, 1993The basic mechanisms of aging and its retardation by caloric restriction (CR) remain unclear. One suggested means by which CR could retard aging is based on production of mitochondrial free radicals, and efficiency of their subsequent metabolism. Currently, there is little information concerning the influences of age and CR on the rates of in vivo ...
R J, Feuers, R, Weindruch, R W, Hart
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