Results 141 to 150 of about 492,470 (313)

Fatty Acid Composition, Steroid Content, In Vitro Antioxidant and Antidiabetic Potentials of Citrullus lanatus and Carica papaya Seed Oils

Biology, Medicine & Natural Product Chemistry
Plant-derived oils rich in bioactive constituents have attracted attention as potential antioxidant and antidiabetic agents. The present study assessed the phytochemical profile, antioxidant activity, enzyme inhibitory activity, and fatty acid profile of
Bamidele Martin Amos-Tautua, Imomotimi Timipa Ajoko, Rafiu Oladiran Raji   +2 more
doaj   +1 more source

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

Advanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg, F. Max Yavitt, Ezgi Bakirci, Khoon Lim, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +5 more
wiley   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source

Study of antioxidant activity of sheep visceral protein hydrolysate: Optimization using response surface methodology

ARYA Atherosclerosis, 2014
BACKGROUND: The main objective of this experiment was optimal use of none edible protein source to increase nutritional value of production with high biological function, including antioxidant activity. METHODS: Sheep visceral (stomach and intestine) was
Nasim Meshginfar, Alireza Sadeghi-Mahoonak, Aman Mohammad Ziaiifar, Mohammad Ghorbani, Mahdi Kashaninejad   +4 more
doaj  

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

Phytochemical Screening and in vivo antioxidant activity of Ethanolic extract of caesalpinia bondus (L.) Roxb [PDF]

, 2012
Phytochemical screening, antioxidant activity in vivo and lipid peroxidation of 75 % ethanolic extract of young twigs and leaves of Caesalpinia bonduc were carried out by chemical test, and assessment of catalase and peroxidase activities and lipid ...
Akindahunsi , A. A, Ntube , C. A, Ogunlana , O. E, Ogunlana , O. O, Olagunju , J. A   +4 more
core   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source