Results 31 to 40 of about 469,771 (267)

Effects of 21-aminosteroid U-74389g on amiodarone-induced pulmonary toxicity in rats [PDF]

open access: yesArchives of the Balkan Medical Union, 2019
Introduction. The widely used antiarrhythmic amiodarone (AD) has been linked to many health problems, including pulmonary toxicity. The objective of the study.
Galya Ts. STAVREVA   +3 more
doaj   +1 more source

Ecotoxicological Assessment of a Glyphosate-Based Herbicide in Cover Plants: Medicago sativa L. as a Model Species

open access: yesApplied Sciences, 2020
Despite the several innovations that have been incorporated in agriculture, the use of herbicides, especially glyphosate (GLY), is still the major tool for weed control.
Beatriz Fernandes   +8 more
doaj   +1 more source

The antioxidant system enzymes’ activity in rats’ brain, intoxicated with sodium fluoride in subtoxic doses [PDF]

open access: yesArchives of the Balkan Medical Union, 2018
The aim of the study was to assess the activity of enzymes in the antioxidant system in the brain of rats subjected to intoxication with sodium fluoride in subtoxic doses. Methods. The studies were conducted on sexually mature Wistar rats weighing 180-
Irina BAGMUT   +4 more
doaj   +1 more source

A Defect in the Antioxidant Defense System in Schizophrenia

open access: yesNeuropsychobiology, 2009
<i>Objectives:</i> Several oxidants and antioxidants have been evaluated in schizophrenia. However, previous studies frequently focused on individual parameters. Determination of the total oxidant and antioxidant status may be more useful.
Virit, O   +7 more
openaire   +5 more sources

Post-Treatment of Synthetic Polyphenolic 1,3,4 Oxadiazole Compound A3, Attenuated Ischemic Stroke-Induced Neuroinflammation and Neurodegeneration

open access: yesBiomolecules, 2020
Ischemic stroke is categorized by either permanent or transient blood flow obstruction, impeding the distribution of oxygen and essential nutrients to the brain.
Arooj Mohsin Alvi   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Antioxidant Systems and Oxidative Stress in the Testes [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2008
Spermatogenesis is an extremely active replicative process capable of generating approxi mately 1,000 sperm a second. The high rates of cell division inherent in this process imply correspondingly high rates of mitochondrial oxygen consumption by the germinal epithelium. However, the poor vascularization of the testes means that oxygen tensions in this
Aitken, R. John, Roman, Shaun D.
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

ANTIOXIDANT STATUS AND LIPID PEROXIDATION IN HEREDITARY HEMOLYTIC ANEMIA IN CHILDREN

open access: yesПаёми Сино
Objective: To examine the parameters of lipid peroxidation (LPO) and antioxidant system (AOS) in children with hereditary hemolytic anemia (HHA). Methods: A study was conducted in the Pediatric Hematology Department of the National Medical Center ...
K.I. ISMOILOV   +3 more
doaj   +1 more source

Melatonin Stimulates Activities and Expression Level of Antioxidant Enzymes and Preserves Functionality of Photosynthetic Apparatus in Hickory Plants (Carya cathayensis Sarg.) under PEG-Promoted Drought

open access: yesAgronomy, 2019
Nowadays, drought is one of the major abiotic factors which negatively affects growth and development of several fruit tree species, including Chinese hickory plants (Carya cathayensis Sarg.). The present investigation was conducted to study the possible
Junfeng Wang   +7 more
doaj   +1 more source

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