Results 121 to 130 of about 28,997 (288)

Cell death mechanisms in Leishmania amazonensis triggered by methylene blue-mediated antiparasitic photodynamic therapy

open access: green, 2018
Débora Picanço Aureliano   +5 more
openalex   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

open access: yesChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Design, Optimized Synthesis, and Coordination Behavior of Quinolinic Benzimidazoles with Cu(II) and Ni(II): Reactivity Toward ROS, Computational Studies, and Biological Profiling

open access: yesEuropean Journal of Inorganic Chemistry, Volume 28, Issue 35, December 9, 2025.
Synthesis and characterization of quinolinic benzimidazole Cu(II) and Ni(II) complexes reveal contrasting reactive oxygen species interactions and selective anticancer activity, highlighting a prodrug‐like mechanism. This study provides new insights into designing redox‐active metal complexes for targeted cancer therapeutics Benzimidazole is a well ...
Lorenzo Verderi   +3 more
wiley   +1 more source

Synthesis of leading chalcones with high antiparasitic, against Hymenolepis nana, and antioxidant activities

open access: gold, 2018
José Tomás Díaz-Carrillo   +6 more
openalex   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang   +17 more
wiley   +1 more source

Bioaccumulation and Depuration of Emamectin Benzoate and Oxytetracycline in the European Black Sea Cucumber (Holothuria forskali): Implications for Aquaculture Integration

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
European black sea cucumber (Holothuria forskali) used in bioaccumulation and depuration trials after ingesting salmon pellets treated with veterinary therapeutants emamectin benzoate and oxytetracycline. The study provides the first kinetic data for these veterinary residues in this species, supporting responsible integration of deposit‐feeders into ...
Thomas Juhasz‐Dora   +6 more
wiley   +1 more source

Zingiber officinale (Ginger), Curcuma longa (Turmeric) and Cymbopogon nardus (Lemon Grass) Essential Oils Have Anti‐Dactylogyrideans Potential in Colossoma macropomum Cuvier 1816 (Tambaqui)

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
ABSTRACT Essential oils are composed of secondary metabolites derived from medicinal plants and have bioactive properties, such as antiparasitic activity. This study investigated the in vitro anti‐dactylogyridean efficacy of the Zingiber officinale, Curcuma longa and Cymbopogon nardus essential oils, as well as the acute toxicity for Colossoma ...
João G. R. Luz   +6 more
wiley   +1 more source

Cognitive Manifestations of Racemose Neurocysticercosis: A Two Case Report

open access: yesAlzheimer's &Dementia, Volume 21, Issue S3, December 2025.
Abstract Background Neurocysticercosis (NCC) is a central nervous system infection caused by the larval form of the tapeworm Taenia solium, endemic in Latin America and Asia. It can present as intraparenchymal or racemose (rNCC) forms, with symptoms including epilepsy, headaches, and intracranial hypertension.
Marcelo Jobet   +4 more
wiley   +1 more source

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