Results 141 to 150 of about 40,838 (333)

Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens [PDF]

, 2014
Jasmine Warfield, William N. Setzer, Ifedayo Victor Ogungbe   +2 more
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Efficacy of antiparasitics on amblyomma sculptum in vitro and in the semi-field: comparative study to ripicephalus microplus

, 2022
Gustavo Henrique Montesião de Sousa
openalex   +1 more source

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová, Šárka Štěpánková, Eva Frýbová, Klára Konečná, Jana Korbielová, Markéta Švarcová, Ondřej Janďourek, Václav Pflégr, Szilvia Bősze, Martin Krátký   +9 more
wiley   +1 more source

Editorial: Chemical ecology of arthropods, plants, and fungi: bioactivity and importance of natural products

Frontiers in Ecology and Evolution, 2023
Srećko Ćurčić, Ljubodrag Vujisić, Milica Ljaljević Grbić, Antoaneta Trendafilova   +3 more
doaj   +1 more source

Cell death mechanisms in Leishmania amazonensis triggered by methylene blue-mediated antiparasitic photodynamic therapy

, 2018
Débora Picanço Aureliano, José Ângelo Lauletta Lindoso, Sandra Regina de Castro Soares, C F H Takakura, Thiago Martini Pereira, Martha S. Ribeiro   +5 more
openalex   +2 more sources

Cryptosporidium parvum hijacks a host’s long noncoding RNA U90926 to evade intestinal epithelial cell-autonomous antiparasitic defense [PDF]

, 2023
Marion L. Graham, Min Li, Ai‐Yu Gong, Silu Deng, Kehua Jin, Shuhong Wang, Xian‐Ming Chen   +6 more
openalex   +1 more source

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

Pharmacological Research, 2020
Mingyan Tang, Xiaodong Hu, Yi Wang, X. Yao, Wei Zhang, Chen-Yea Yu, Fuying Cheng, Jiang-yan Li, Q. Fang   +8 more
semanticscholar   +1 more source

Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard, Ivanildo A. Brito, Emerson A. Oliveira, Mariana H. Chaves, João Henrique G. Lago   +4 more
wiley   +1 more source

Intranasal Administration of aSchistosoma mansoniGlutathioneS-Transferase-Cholera Toxoid Conjugate Vaccine Evokes Antiparasitic and Antipathological Immunity in Mice [PDF]

, 1999
Jiabin Sun, Nathalie Mielcarek, Mekuria Lakew, Jean‐Marie Grzych, A Capron, Jan Holmgren, Cécil Czerkinsky   +6 more
openalex   +1 more source