Results 231 to 240 of about 28,997 (288)
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2013
: The most important parasitic diseases, malaria, leishmaniasis, trypanosomiasis, and schistosomiasis, are a great burden to mankind, threatening the life of millions of people worldwide and mostly affecting the poorest. Because drug resistance is increasing and vaccines are rarely available, novel chemotherapeutic compounds are necessary in order to ...
Jette, Pretzel +3 more
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: The most important parasitic diseases, malaria, leishmaniasis, trypanosomiasis, and schistosomiasis, are a great burden to mankind, threatening the life of millions of people worldwide and mostly affecting the poorest. Because drug resistance is increasing and vaccines are rarely available, novel chemotherapeutic compounds are necessary in order to ...
Jette, Pretzel +3 more
openaire +2 more sources
Delivery strategies for antiparasitics
Expert Opinion on Investigational Drugs, 2003Optimisation of drug carrier systems and drug delivery strategies that take into account the peculiarities of individual infectious agents and diseases are key elements of modern drug development. In the following, different aspects of a rational design for antiparasitic drug formulation will be reviewed, covering delivery systems such as nano- and ...
Oliver, Kayser, Albrecht F, Kiderlen
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Mayo Clinic Proceedings, 1992
Several important developments have occurred in recent years in the chemotherapy for and prophylaxis of parasitic infections. Although mefloquine is clearly the most effective agent for prevention of chloroquine-resistant falciparum malaria, its use has been compromised by side effects, both real and imagined. Well-designed studies have shown that side
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Several important developments have occurred in recent years in the chemotherapy for and prophylaxis of parasitic infections. Although mefloquine is clearly the most effective agent for prevention of chloroquine-resistant falciparum malaria, its use has been compromised by side effects, both real and imagined. Well-designed studies have shown that side
openaire +3 more sources
Praziquantel: The enigmatic antiparasitic
Parasitology Today, 1992Praziquantel (PZQ), a pyrazinoisoquinoline, was introduced as a novel anthelmintic in 1975. PZQ is currently the drug of choice for the treatment of a wide range of both veterinary and human trematode and cestode infections, including human schistosomiasis.
T A, Day, J L, Bennett, R A, Pax
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Antiparasitic Therapy in Children
Pediatric Clinics of North America, 2005Treatment of parasitic infections in children presents many challenges for the clinician. Although parasitic infections are ubiquitous on a worldwide basis, with an estimated 1 billion persons infected with intestinal helminthes alone, physicians in the United States and other developed countries are often unfamiliar with the management of these ...
Troy D, Moon, Richard A, Oberhelman
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Antiparasitic thiocyanatobenzothiazoles
Journal of Medicinal Chemistry, 1974Robert J. Alaimo +3 more
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2016
Abstract This chapter provides a systematic summary of antiparasitic agents, grouped by class and mechanism of action. Each summary provides information on the mode of action, resistance mechanisms, pharmacology, and clinical use.
M. Estée Török +2 more
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Abstract This chapter provides a systematic summary of antiparasitic agents, grouped by class and mechanism of action. Each summary provides information on the mode of action, resistance mechanisms, pharmacology, and clinical use.
M. Estée Török +2 more
openaire +1 more source
Ivermectin, a potential anticancer drug derived from an antiparasitic drug
Pharmacological Research, 2021Xin Yao, Qiang Fang
exaly