Understanding the role of alkaline phosphatase as a possible marker for the evaluation of antiparasitic agents [PDF]
Gustavo A. Martı́nez, Luis E Trujillo
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Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities
This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
José Walber Gonçalves Castro +3 more
wiley +1 more source
A review study of therapeutic effects of Peganum harmala [PDF]
Peganum harmala. belongs to Asian Origin and grows in the Middle East and in part of South mainly in India and Pakistan, is a plant of the family Nitrariaceae. It is a perennial plant which can grow to about 0.8 m tall.
Miraj, S.
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Studies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agents [PDF]
Stephen P. Muench +7 more
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ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti +8 more
wiley +1 more source
Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes [PDF]
Objectives The disease alveolar echinococcosis (AE), caused by the larval stage of the cestode Echinococcus multilocularis, is fatal if treatment is unsuccessful.
Hemphill, Andrew +3 more
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ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira +7 more
wiley +1 more source
Synthesis and in vitro biological activity of chalcone derivatives as potential antiparasitic agents [PDF]
Koketso J. Setshedi +5 more
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Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent
Edmund V. Capparelli +4 more
semanticscholar +1 more source
ABSTRACT Quinoxaline is an aza‐heterocycle found in some bioactive compounds. Thus, to enhance the pharmacological scope of this nucleus, we report a series of 19 acetamides decorated with a quinoxaline core. The synthesis involved the linkage of previously constructed bromoacetamides and hydroxyphenyl quinoxalines via an SN2 reaction. The first series
Cesar E. Tovar‐Roman +2 more
wiley +1 more source

