Results 41 to 50 of about 24,731 (282)
Background. The detection of antiphospholipid antibodies (aPL) is of interest because of their importance in the pathogenesis of arterial or venous thrombosis. They could be a “second hit” of an inflammatory event such as infection.
Amal Abouda+8 more
doaj +1 more source
xTrimoABFold: De novo Antibody Structure Prediction without MSA [PDF]
In the field of antibody engineering, an essential task is to design a novel antibody whose paratopes bind to a specific antigen with correct epitopes. Understanding antibody structure and its paratope can facilitate a mechanistic understanding of its function.
arxiv
Antiphospholipid Antibodies in Stillbirth [PDF]
To compare antiphospholipid antibodies in deliveries with and without stillbirth using a multicenter, population-based case-control study of stillbirths and live births.Maternal sera were assayed for immunoglobulin (Ig)G and IgM anticardiolipin and anti-β2-glycoprotein-I antibodies.
Marian Willinger+15 more
openaire +3 more sources
On Pre-trained Language Models for Antibody [PDF]
Antibodies are vital proteins offering robust protection for the human body from pathogens. The development of general protein and antibody-specific pre-trained language models both facilitate antibody prediction tasks. However, there have been limited studies that comprehensively explore the representation capability of distinct pre-trained language ...
arxiv
Antiphospholipid antibodies and infections [PDF]
Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as "autoimmune" and "infectious" types. This distinction, however, has subsequently been found not to be absolute.
R Cervera, Ronald A. Asherson
openaire +3 more sources
Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou+2 more
wiley +1 more source
Abstract Objective To explore the correlation between antinuclear antibodies (ANAs) and pregnancy loss (PL), and to observe its impact on the pregnancy outcomes of in vitro fertilization/intracytoplasmic sperm injection‐embryo transfer (IVF/ICSI‐ET) in recurrent PL (RPL) patients. Methods In this retrospective study, patients first seen at the hospital
Manman Liu+8 more
wiley +1 more source
Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody [PDF]
Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that have evolved resistance.
arxiv +1 more source
Etanercept and venous thromboembolism: a case series
Introduction The treatment with antitumor necrosis factor agents has often been associated with the induction of autoantibodies (antinuclear antibodies, anti-double stranded DNA antibodies and antiphospholipid antibodies).
Guggenheim Carla+3 more
doaj +1 more source
Marino Paroli,1 Alessandro Polidoro,1 Simone Romano,1 Daniele Accapezzato21Department of Biotechnology and Medical-Surgical Sciences, 2Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, ItalyAbstract: We report on
Paroli M+3 more
doaj