Results 251 to 260 of about 3,407,318 (341)

Heyde Syndrome: A Literature Review

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Heyde syndrome, a triad of anemia from gastrointestinal (GI) bleeding, aortic valve stenosis, and acquired von Willebrand syndrome, primarily affects individuals over 65. Management requires a multidisciplinary approach, including medical therapy, endoscopic intervention, and valve replacement.
Yashika Gupta   +12 more
wiley   +1 more source

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 2, Page 509-515, February 2026.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi   +8 more
wiley   +1 more source

Venous Thromboembolism in Aggressive B‐Cell Lymphoma Patients Treated with CD19 CAR‐T Therapy: Single‐Institution Study

open access: yeseJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Background Large B‐cell lymphomas (LBCLs) are a common subtype of non‐Hodgkin lymphomas. CD19 chimeric antigen receptor T‐cell (CAR‐T) therapy has revolutionized LBCL treatment, with high remission rates but also significant toxicities, including cytokine release syndrome (CRS) and immune effector cell‐associated neurotoxicity syndrome (ICANS).
Neha Venkatesh   +9 more
wiley   +1 more source

Metabolic Dysfunction and Coronary Plaque Vulnerability: The Predictive Role of Insulin Resistance Indices in Cardiovascular Outcomes

open access: yesMedComm, Volume 7, Issue 2, February 2026.
ABSTRACT Significant residual cardiovascular risk persists in patients diagnosed with coronary artery disease despite intensive lipid‐lowering therapy. Although insulin resistance (IR) is an established epidemiological risk factor, the biological mechanisms by which it promotes plaque destabilization remain poorly understood.
Yue Yu   +11 more
wiley   +1 more source

The Association Between Levels of Post‐Discharge Care Continuity and Long‐Term Treatment Adherence and Anxiety‐Depressive Symptoms in Myocardial Infarction Patients: A Retrospective Cohort Study

open access: yesNursing Open, Volume 13, Issue 2, February 2026.
ABSTRACT Background Post‐discharge care continuity represents a modifiable factor influencing outcomes in myocardial infarction survivors, yet its multidimensional relationship with treatment adherence and psychological morbidity remains underexplored.
Yanhui Hou   +3 more
wiley   +1 more source

On‐Resin Pictet–Spengler Cyclization for 1,2,3,4‐Tetrahydro‐β‐carboline‐3‐carboxylate (Tcc) Peptide Synthesis With Acid‐Labile Functional Tolerance

open access: yesJournal of Peptide Science, Volume 32, Issue 2, February 2026.
The constrained tryptophan (Trp) analog 1,2,3,4‐tetrahydro‐β‐carboline‐3‐carboxylic acid (Tcc) is used to restrict peptide conformation in structure–activity relationship studies. Although Pictet–Spengler cyclization of Trp and aldehydes with mineral acid gives Tcc analogs, such harsh conditions do not tolerate acid‐labile functionality.
Omer S. L. N'dri   +10 more
wiley   +1 more source

Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith   +5 more
wiley   +1 more source

Efficient α‐Selective Chlorination of Meta‐ and Ortho‐Substituted Phenylacetic Acids

open access: yesChemistrySelect, Volume 11, Issue 6, 12 February 2026.
A series of novel ortho‐ and meta‐substituted alpha‐chlorophenylacetic acids was prepared by efficient chlorination at the benzylic position with TCCA under solvent free conditions. Competing electrophilic aromatic chlorination did not occur with electron‐withdrawing or weakly electron‐donating ring substituents. The title compounds are synthons with a
Alessandro Giraudo   +7 more
wiley   +1 more source

High Rates of Defect Closure After Resection of Large Nonpedunculated Colorectal Lesions Using a Through‐The‐Scope Clip With Anchor Prongs

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Prophylactic complete closure of mucosal defects after resection of gastrointestinal lesions is key to reducing delayed bleeding, but complete closure for large defects can be challenging with conventional through‐the‐scope clips (TTSC).
Daniel von Renteln   +11 more
wiley   +1 more source

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