Results 251 to 260 of about 3,407,318 (341)
Heyde Syndrome: A Literature Review
ABSTRACT Background and Aims Heyde syndrome, a triad of anemia from gastrointestinal (GI) bleeding, aortic valve stenosis, and acquired von Willebrand syndrome, primarily affects individuals over 65. Management requires a multidisciplinary approach, including medical therapy, endoscopic intervention, and valve replacement.
Yashika Gupta +12 more
wiley +1 more source
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi +8 more
wiley +1 more source
The nature of antiplatelet activity in antilymphoblast ALG--with special reference to cross-reacting antibody, immunochemical characterization, and Coombs' positive thrombocytopenia in ALG-treated renal recipients. [PDF]
Amemiya, H +4 more
core
ABSTRACT Background Large B‐cell lymphomas (LBCLs) are a common subtype of non‐Hodgkin lymphomas. CD19 chimeric antigen receptor T‐cell (CAR‐T) therapy has revolutionized LBCL treatment, with high remission rates but also significant toxicities, including cytokine release syndrome (CRS) and immune effector cell‐associated neurotoxicity syndrome (ICANS).
Neha Venkatesh +9 more
wiley +1 more source
ABSTRACT Significant residual cardiovascular risk persists in patients diagnosed with coronary artery disease despite intensive lipid‐lowering therapy. Although insulin resistance (IR) is an established epidemiological risk factor, the biological mechanisms by which it promotes plaque destabilization remain poorly understood.
Yue Yu +11 more
wiley +1 more source
ABSTRACT Background Post‐discharge care continuity represents a modifiable factor influencing outcomes in myocardial infarction survivors, yet its multidimensional relationship with treatment adherence and psychological morbidity remains underexplored.
Yanhui Hou +3 more
wiley +1 more source
The constrained tryptophan (Trp) analog 1,2,3,4‐tetrahydro‐β‐carboline‐3‐carboxylic acid (Tcc) is used to restrict peptide conformation in structure–activity relationship studies. Although Pictet–Spengler cyclization of Trp and aldehydes with mineral acid gives Tcc analogs, such harsh conditions do not tolerate acid‐labile functionality.
Omer S. L. N'dri +10 more
wiley +1 more source
Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith +5 more
wiley +1 more source
Efficient α‐Selective Chlorination of Meta‐ and Ortho‐Substituted Phenylacetic Acids
A series of novel ortho‐ and meta‐substituted alpha‐chlorophenylacetic acids was prepared by efficient chlorination at the benzylic position with TCCA under solvent free conditions. Competing electrophilic aromatic chlorination did not occur with electron‐withdrawing or weakly electron‐donating ring substituents. The title compounds are synthons with a
Alessandro Giraudo +7 more
wiley +1 more source
ABSTRACT Background Prophylactic complete closure of mucosal defects after resection of gastrointestinal lesions is key to reducing delayed bleeding, but complete closure for large defects can be challenging with conventional through‐the‐scope clips (TTSC).
Daniel von Renteln +11 more
wiley +1 more source

