Results 221 to 230 of about 82,766 (300)

Impaired platelet activation in patients with hereditary deficiency of p47phox [PDF]

, 2018
Azzari, Chiara, Bartimoccia, Simona, Carnevale, Roberto, Loffredo, Lorenzo, Martire, Baldassarre, Nocella, Cristina, Pignata, Claudio, Plebani, Alessandro, Sanguigni, Valerio, Soresina, Annarosa, Violi, Francesco   +10 more
core   +2 more sources

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

Transfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan, Mira Patel, Bryan A. Cotton, Julia Coleman, Donald Jenkins   +4 more
wiley   +1 more source

Influence of Genetic and Epigenetic Factors of P2Y₁₂ Receptor on the Safety and Efficacy of Antiplatelet Drugs. [PDF]

Cardiovasc Drugs Ther
Danielak D, Pawlak K, Główka F, Karaźniewicz-Łada M.   +3 more
europepmc   +1 more source

Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double-blind randomised controlled feasibility trial. [PDF]

BMJ Open, 2020
Desborough MJR, Al-Shahi Salman R, Stanworth SJ, Havard D, Brennan PM, Dineen RA, Coats TJ, Hepburn T, Bath PM, Sprigg N.   +9 more
europepmc   +1 more source

Prothrombin complex concentrate for oral factor Xa inhibitor reversal prior to urgent invasive procedures

Transfusion, EarlyView.
Abstract Background Oral factor Xa (FXa) inhibitors are anticoagulants with no approved reversal agent for use before urgent invasive procedures. Four‐factor prothrombin complex concentrate (4F‐PCC) is used off‐label for this despite limited evidence regarding its effectiveness and safety.
Mohammad Shamiea, Alex Osnis, Awan Kashoua, Orli Avnery, Gilad Itchaki, Shuli Isman, Tali Tohami, Osnat Jarchowsky‐Dolberg, Martin Ellis   +8 more
wiley   +1 more source

Safety and efficacy of dual antiplatelet drugs for stent-assisted embolization on risk of stroke and prognosis in patients with ruptured intracranial aneurysms: One center results of CIAP-5 clinical trial. [PDF]

Interv Neuroradiol
Wang S, Zhang T, Du L, Hu P, Ye M, Sun L, Hong T, Li G, Zhang P, Zhang H, He C.   +10 more
europepmc   +1 more source

Platelet clotting defects in severe trauma identified by a whole blood microfluidic assay

Transfusion, EarlyView.
Abstract Background Hemorrhage is the leading cause of preventable death in severe trauma, with primary hemostasis relying on platelet‐rich clot formation under high shear flow. This study quantifies the incidence, severity, and heterogeneity of platelet dysfunction in Level I trauma patients.
Gian Rivera Crespo, Jack Killinger, Christopher Bresette, Susan M. Shea, David Ku   +4 more
wiley   +1 more source

An innovative modelling proposal for the blood supply chain

Vox Sanguinis, EarlyView.
Abstract Whole‐blood donation and apheresis are the only ways to obtain blood components for human use. Tools are being developed to improve the efficiency of blood donation systems by reducing waste, increasing donations and preventing shortages.
Jorge Pagán‐Ortiz, Josué Pagán, María Luisa Lozano, Vicente Vicente, Francisca Ferrer‐Marín   +4 more
wiley   +1 more source

Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study

Experimental Physiology, EarlyView.
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey, Richard G. Davies, Brenig L. Gwilym, Benjamin S. Stacey, Danny Walmsley, Michael H. Lewis, Josip Butkovic, Ivan Mumlek, Brad Perry, Zvonomir Vrselja, Shigehiko Ogoh, James A. Pawelczyk, Mohamad Bashir, Richard D. White, Ian M. Williams   +14 more
wiley   +1 more source

Delayed Gastric Bleeding in a Patient With Chronic Myeloid Leukemia: A Case of Post‐Biopsy Bleeding

DEN Open, Volume 7, Issue 1, April 2027.
The presence of underlying conditions, particularly malignancies such as myeloproliferative disorders, may increase the risk of delayed bleeding following gastric mucosal biopsy, and similar cases warrant careful accumulation and evaluation in future. ABSTRACT A 76‐year‐old man was referred to our hospital for evaluation of anemia.
Yoko Kosaka, Hiromichi Yamane, Hidekazu Nakanishi, Nagio Takigawa   +3 more
wiley   +1 more source