An integrated general practice and pharmacy-based intervention to promote the use of appropriate preventive medications among individuals at high cardiovascular disease risk: protocol for a cluster randomized controlled trial [PDF]
Background: Cardiovascular diseases (CVD) are responsible for significant morbidity, premature mortality, and economic burden. Despite established evidence that supports the use of preventive medications among patients at high CVD risk, treatment gaps ...
Adina Hayek +50 more
core +4 more sources
Pharmacological effects of raas blockade in ischemic nephropathy [PDF]
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio +8 more
core +1 more source
Metabolism of ticagrelor in patients with acute coronary syndromes. [PDF]
© The Author(s) 2018Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its ...
B Ibanez +41 more
core +2 more sources
S-Nitrosoglutathione reduces asymptomatic embolization after carotid angioplasty [PDF]
Background: The major complication of carotid angioplasty is embolic stroke, which may occur after balloon inflation and deflation or in the early postintervention period.
Clifton, A. +4 more
core +1 more source
A-19 | Abbreviated Versus Prolonged Dual Antiplatelet Therapy (DAPT) Following Percutaneous Coronary Intervention (PCI) with Drug-Eluting Stents (DES): A Meta-Analysis of Randomized Controlled Trials (RCTs) [PDF]
Abdulbaril Olagunju +6 more
openalex +1 more source
The review provides the current information about the role of antiplatelet therapy in the cardiovascular prevention in patients with coronary artery disease and coronary revascularization.
Yu. I. Grinschtein +2 more
doaj +1 more source
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R. +2 more
core +1 more source
One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W. +20 more
core +2 more sources
Introduction: Type 2 diabetes mellitus (T2DM) is an important and common cardiovascular risk factor. The purpose of the study was to evaluate the frequency of use of oral antiplatelet drugs (OAPs) and oral anticoagulant drugs (OACs) among the elderly ...
Beata Łabuz-Roszak +8 more
doaj +1 more source
Newer agents in antiplatelet therapy: a review. [PDF]
Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke.
Holinstat, Michael, Yeung, Jennifer
core +3 more sources

