Results 91 to 100 of about 51,164 (250)

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Effects of Antiplatelet Drugs on Platelet-Dependent Coagulation Reactions. [PDF]

Biomolecules, 2023
Muravlev IA, Dobrovolsky AB, Antonova OA, Khaspekova SG, Alieva AK, Pevzner DV, Mazurov AV.   +6 more
europepmc   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Food‐grade proteins, lipids, and fibers as potential tools to ameliorate cardiovascular disorders: A review

Food Biomacromolecules, EarlyView.
Abstract Cardiovascular diseases (CVDs) remain the leading cause of global mortality, necessitating effective preventive and adjunct therapeutic strategies beyond conventional pharmacological interventions. Although previous reviews have focused on individual nutrients or dietary patterns, this review provides a mechanism‐based, integrative perspective
Sridevi Shanmugam, Rukaiah Fatma Begum, Nirenjen Shanmugasundaram, Bhupendra Gopalbhai Prajapati, Suresh Ankul Singh, Pavithra Nagenthran, Sudarshan Singh, Kesarla Rajesh   +7 more
wiley   +1 more source

Antiplatelet drugs may increase the risk for checkpoint inhibitor-related pneumonitis in advanced cancer patients. [PDF]

ESMO Open, 2023
Araki T, Kanda S, Ide T, Sonehara K, Komatsu M, Tateishi K, Minagawa T, Kiniwa Y, Kawakami S, Nomura S, Okuyama R, Hanaoka M, Koizumi T.   +12 more
europepmc   +1 more source

Risk of hemorrhagic stroke in warfarin‐treated patients following heart valve replacement: Findings from the MAGPIE study

Ibrain, EarlyView.
Among 568 mechanical heart valve replacement patients in Bangladesh, hemorrhagic stroke occurred in 4.4% with 52% mortality. Severe pulmonary hypertension increased risk 4.4‐fold, and warfarin therapy ≥104 months nearly doubled the risk, highlighting the need for long‐term risk monitoring in anticoagulated valve patients.
Dipannita Adhikary, Md. Abdullah Yusuf, AM Nayeem Parvez, Sheikh M. B. Faruque, Santo Barman, Adneen Moureen, Luke J. Rogers, Aziz Momin, Venkatachalam Chandrasekaran, Asit B. Adhikary, Redoy Ranjan   +10 more
wiley   +1 more source

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard, Akhil Rekulapelli, Riley S. Gilbertson, Connor S. Charton, William F. Hefley, Michael J. Colello, Jennifer L. Halpern, Herbert S. Schwartz, Daniel J. Johnson, Jonathan G. Schoenecker, Joshua M. Lawrenz   +10 more
wiley   +1 more source

Patients with metabolic dysfunction-associated steatotic liver disease have preserved in vitro responses to antiplatelet drugs. [PDF]

Res Pract Thromb Haemost, 2023
van den Boom BP, van Beek AP, Adelmeijer J, Blokzijl H, Lisman T.   +4 more
europepmc   +1 more source

Mechanisms and recent advances in non-coding RNAs and RNA modifications in antiplatelet drug resistance

Frontiers in Genetics
The high incidence and mortality rates of cardiovascular and cerebrovascular diseases make them a significant global health challenge. Antiplatelet drugs play a central role in the prevention and treatment of these diseases.
Ping Ni, Ping Ni, Kejie Chen, Jing Xiang, Jing Xiang, Haifeng Shao, Xiaoling Chen, Qiao Chen, Lingling Wang, Junli Hao, Xinyi Huang, Qing Cao, Yali Yang, Quandan Tan, Jie Yang, Suping Li   +15 more
doaj   +1 more source

METTL14 Regulates Myocardial Infarction Progression via m6A‐Dependent Modulation of OTUD1‐Mediated Deubiquitination of DUSP6

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei, Ya‐Fang Shen, Jin‐Yu Zhang   +2 more
wiley   +1 more source