Results 121 to 130 of about 5,245,251 (341)

Antiplatelet Therapy in Ischemic Stroke and Transient Ischemic Attack.

Stroke, 2019
Stroke is a leading cause of mortality and disability worldwide. Initial manifestations of acute cerebral ischemia, such as ischemic stroke and transient ischemic attack (TIA), are often followed by recurrent vascular events, including recurrent stroke ...
D. Hackam, J. Spence
semanticscholar   +1 more source

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
wiley   +1 more source

Rationale and Design of the CREATE Trial: A Multicenter, Randomized Comparison of Continuation or Cessation of Single Antithrombotic Therapy at 1 Year After Transcatheter Aortic Valve Replacement

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Current guidelines and expert consensus recommend lifelong single antiplatelet therapy for patients undergoing transcatheter aortic valve replacement who have no indication for anticoagulation or dual antiplatelet therapy. However, there is no
Ran Liu, Yang Li, Lihua Zhang, Zhinan Lu, Zhaolin Fu, Thomas Modine, Hasan Jilahawi, Stuart Pocock, Yongjian Wu, Guangyuan Song   +9 more
doaj   +1 more source

Selection of medication in hospitalised elderly patients with Angina Pectoris [PDF]

, 2004
Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting:
Cacciottolo, Joseph M., Gauci, Marise, McElnay, James C.   +2 more
core  

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]

, 2016
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W., Amarenco, Pierre, Bornstein, Natan M., Canhão, Patrícia, Caplan, Louis R., Donnan, Geoffrey A., Ferro, José M., Hennerici, Michael G., Labreuche, Julien, Lavallée, Philippa C., Molina, Carlos, org Steering Committee, T. I. A. r. e. g. i. s. t. r. y., Rothwell, Peter M., Sissani, Leila, Steg, Philippe Gabriel, Toni, Danilo, Touboul, Pierre Jean, Uchiyama, Shinichiro, Vicaut, Éric, Wong, Lawrence K. S., Školoudík, David   +20 more
core   +2 more sources

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

The preventive effect of antiplatelet therapy in acute respiratory distress syndrome: a meta-analysis

Critical Care, 2018
Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition with high mortality that imposes a serious medical burden. Antiplatelet therapy is a potential strategy for preventing ARDS in patients with a high risk of developing ...
Yingqin Wang, Ming Zhong, Zhichao Wang, Jieqiong Song, Wei Wu, Duming Zhu   +5 more
doaj   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

The Use of Antihypertensive and Antiplatelet Drugs on Hospital Stroke Patients [PDF]

, 2016
Medicine is one of the most important part of the healing process, the restoration of health and prevention of disease. This study aims to describe the use of drugs, particularly antihypertensive and antiplatelet drugs in stroke patients hospitalized in ...
Abdullah, A. (Akrom), Budiyono, B. (Budiyono), Putri, A. R. (Anggy)   +2 more
core  

Paraneoplastic thrombocytosis in ovarian cancer [PDF]

, 2012
<p>Background: The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear.</p> <p>Methods: We analyzed clinical data on 619 patients with epithelial ...
Akl EA, Alpa M. Nick, Angela F. Drew, Anil K. Sood, Bulent Ozpolat, Chad V. Pecot, Charles N. Landen, Diana Urbauer, Donald Lamkin, Edward H. Ahn, Erin R. King, Frances Balkwill, Francisca Gushiken, Gabriel Lopez-Berestein, Guillermo N. Armaiz-Pena, Hannah Gershenson, Hee Dong Han, Hernan G. Vasquez, Iain A. McNeish, Ibrahim Tekedereli, Jermaine Coward, Justin Bottsford-Miller, Katherine Collins, Koen DeGeest, Koji Matsuo, Mian M.K. Shahzad, Michael T. Deavers, Rajesha Rupaimoole, Rebecca L. Stone, Riess L, Rui Wang, Susan K. Lutgendorf, Vahid Afshar-Kharghan, Virginia K. Bond, Wah Chiu, Wei Hu   +35 more
core   +1 more source