Results 221 to 230 of about 101,135 (306)

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari   +6 more
wiley   +1 more source

Impact of Left Bundle Branch Area Pacing on Echocardiographic Parameters and Symptoms: Data From the Conduction System Pacing Italian Network Group (C‐SING) Study

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Left bundle branch area pacing is associated with preservation of ventricular function in patients with bradycardia indications and with significant reverse remodeling and symptomatic improvement in patients with heart failure. Maintaining a high percentage of effective LBBAP capture is critical to minimize the risk of pacing‐induced cardiomyopathy and
Gabriele Dell'Era   +32 more
wiley   +1 more source

Zero‐Contrast Versus Contrast‐Guided Left Atrial Appendage Occlusion: A Comparative Analysis of Procedural and Long‐Term Outcomes

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Zero‐contrast left atrial appendage occlusion yielded high procedural success and similar periprocedural adverse event rates compared to the contrast‐guided approach. At 45‐day follow‐up, successful LAA closure (defined as peri‐device leak ≤ 5 mm) and device‐related thrombus rates were similar.
Joe Demian   +12 more
wiley   +1 more source

Implementation of a Standardized Nurse‐Guided Heparinization Protocol Improves Anticoagulation During Left Atrial Ablation Procedures

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
A standardized, nurse‐led heparinization protocol significantly improves the speed, consistency, and precision of achieving therapeutic ACT levels during left atrial ablation, while reducing excessive anticoagulation and maintaining a comparable safety profile to conventional operator‐guided dosing.
Vanessa Sciacca   +14 more
wiley   +1 more source

Adherence to Dual Antiplatelet Therapy Protocol in Acute Ischemic Stroke. [PDF]

open access: yesEur J Neurol
Martikainen L   +7 more
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibition and injection burden in mild diabetic macular edema: An exploratory post hoc analysis of the COMET trial

open access: yesJournal of Diabetes Investigation, EarlyView.
Combining oral sodium‐glucose cotransporter 2 inhibitors with reduced intravitreal injections of anti‐vascular endothelial growth factor showed potential efficacy for mild diabetic macular edema. ABSTRACT Aims To investigate the potential of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as a less invasive treatment option for mild diabetic macular
Yoko Takatsuna   +6 more
wiley   +1 more source

Dapagliflozin does not impair microvascular hemorheology in type 2 diabetes mellitus: A multicenter randomized controlled trial (D‐PATH study)

open access: yesJournal of Diabetes Investigation, EarlyView.
Graphical abstract illustrating the study design, physiological rationale, and key findings of the D‐PATH trial. Dapagliflozin, an SGLT2 inhibitor, lowers HbA1c and body weight while increasing hematocrit and erythropoietin levels. Although an elevated hematocrit could theoretically increase blood viscosity and impair microcirculatory flow, ex vivo ...
Yuki Nakatani   +16 more
wiley   +1 more source

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