Exploring Brain Parenchymal Changes in Acromegaly: Focus on White Matter Hyperintensities
ABSTRACT Introduction Acromegaly is a rare chronic disease caused by excessive secretion of growth hormone. Even with biochemical control, hormonal imbalance may lead to cerebral changes. This study aimed to evaluate the presence of white matter hyperintensities (WMHs) in patients with acromegaly.
Denise Costa +7 more
wiley +1 more source
Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry. [PDF]
Noseda R +32 more
europepmc +1 more source
Determination of platelet function in patients with cerebral infarction on antiplatelet therapy
Tadatoshi Komiya +3 more
openalex +2 more sources
Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki +3 more
wiley +1 more source
Proton pump inhibitors have no effect on short or long term rebleeding or mortality in patients with overt gastrointestinal bleeding. [PDF]
Mrad J +13 more
europepmc +1 more source
ABSTRACT Background Polycythemia vera (PV) and essential thrombocythemia (ET) are associated with a well‐recognized increased risk of thrombotic events, bleeding, and all‐cause mortality, but the frequency of these outcomes during treatment has rarely been assessed in large cohorts.
Anneli Enblom Larsson +5 more
wiley +1 more source
Comparison of the antiplatelet effect of clopidogrel hydrogeno sulfate and clopidogrel besylate in patients with stable coronary artery disease [PDF]
M. C. Chamilos +7 more
openalex +1 more source
TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni +7 more
wiley +1 more source
Bleeding Risk With Combining Antiplatelets and Anticoagulants for Secondary Stroke Prevention: A Propensity Score-Matched Analysis. [PDF]
Farrokh S +5 more
europepmc +1 more source
ABSTRACT Background The clinical focus of haemophilia has expanded beyond bleeding outcomes to encompass long‐term comorbidities such as cardiovascular disease (CVD). However, it remains unclear when vascular changes begin in this population. Carotid intima‐media thickness (cIMT), a validated, non‐invasive marker of subclinical atherosclerosis, may ...
Alyson Trillo +5 more
wiley +1 more source

