Results 141 to 150 of about 8,789 (241)

Metformin Inhibits Trophoblast Ferroptosis by Suppressing ATF2 and Activating the PI3K/Akt/Nrf2 Pathway to Improve Gestational Diabetes Mellitus

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia, Yuhui Zhang, Wenjie Liu, Siyu Li, Chenying Zhang, Guangtong She, Huiyan Wang   +6 more
wiley   +1 more source

De Novo Discovery of Bioactive Cyclic Peptides via Cellular Selection of Genetically Encoded Libraries

ChemBioChem, Volume 27, Issue 18, 28 September 2026.
Genetically encoded cyclic peptide libraries can be employed in cellular selection platforms to identify cyclic peptide inhibitors for therapeutic targets by directly selecting for desired biological activities. This review systematically summarizes representative studies and suggests future opportunities for using cellular selection for de novo cyclic
Linwei Yang, Abhijit Behera, Hannah J. Meyers, Tina Wang   +3 more
wiley   +1 more source

Cotton Salt Stress Resilience: Integrating Physiological, Molecular, and Agronomic Strategies for Next-Generation Breeding. [PDF]

Plant Cell Environ
Dilber S, Shao L, Guo H, Dou Y, Nauman M, Li K, Yang R, Qian Y, Guo J, Muchugi A, Botella JR, Jia KP, Miao Y.   +12 more
europepmc   +1 more source

Bioinformatics analysis of the KEA gene family in rice. [PDF]

Open Life Sci
Zhang Z, Dang S.
europepmc   +1 more source

The role of plasma membrane Na+/H+ antiporters in the physiology of yeast cells

, 2007
) r Nhal-type antiporterswith differentsubstratespeciÍicity(or affinityto individualsubstrates) andfunctions.One of themis involvedin thedetoxificationof cells andtheothercouldplay an importantrole in the maintenanceof stableintracellularpotassiumcontent,
Papoušková, Klára
core  

Editorial for the Special Issue "Microorganisms in Agriculture". [PDF]

Microorganisms
Chen WC.
europepmc   +1 more source

Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies. [PDF]

Plant Signal Behav
Das S, Janeeshma E, Mousavi H, Aronsson H, Sarraf M.   +4 more
europepmc   +1 more source

<i>Arabidopsis</i> Antiporter Genes as Targets of NO Signalling: Phylogenetic, Structural, and Expression Analysis. [PDF]

Int J Mol Sci
Amir R, Qayyum Z, Hussain S, Yun BW, Hussain A, Mun BG.   +5 more
europepmc   +1 more source

Dual roles of SOS1: Na⁺ extrusion and vacuolar compartmentation. [PDF]

Plant Commun
Qi Y, Qiu QS.
europepmc   +1 more source

Draft genome sequence of <i>Bacillus velezensis</i> CMAA1918 isolated from the rhizosphere of drought-tolerant plant <i>Neoglaziovia variegata</i>. [PDF]

Microbiol Resour Announc
Lacerda-Júnior GV, Melo IS.
europepmc   +1 more source