Results 121 to 130 of about 8,789 (241)

The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit, Kornkamon Lertsuwan, Natnicha Tannop, Ploypapus Lapatkeattisukul, Thanayuth Jenpichitkulchai, Nittiyaporn Sotapong, Jarinthorn Teerapornpuntakit, Tueanjai Khunluck, Siriwan Punvilai, Narattaphol Charoenphandhu   +9 more
wiley   +1 more source

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE‐Mediated Renal Drug‐Drug Interactions in Healthy Volunteers

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1016-1026, October 2026.
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová, Fabian Müller, Daniel Auge, Jörg König, Martin F. Fromm, Arne Gessner   +5 more
wiley   +1 more source

CG1607 and CG9413, two not-yet-described SLC7 amino acid antiporters. Role in developmental progression and growth control

, 2016
CG1607 and CG9413, two not-yet-described SLC7 amino acid antiporters. Role in developmental progression and growth control. 30.
Galagovsky, Diego, Depetris-Chauvin, Ana, Grosjean, Yaël   +2 more
core   +2 more sources

ArgT functions as an arginine transporter in Staphylococcus aureus

Journal of Bacteriology
Glycolytic activity is required for Staphylococcus aureus (S. aureus) to establish an infection. These data indicate that carbon catabolite repression, mediated by CcpA, is active during the initial stages of infection.
Gabrielle F. Schulze, Itidal Reslane, Fareha Razvi, Luke D. Handke, McKenzie K. Lehman, Paul D. Fey   +5 more
doaj   +1 more source

Coat Color‐Associated Transcriptomic Differences of Black and White Hortobágyi Racka Sheep Using the RNA‐Seq Technique

Ecology and Evolution, Volume 16, Issue 10, October 2026.
We compared skin transcriptomes of black‐ and white‐coated Hortobágyi Racka sheep using RNA‐seq to identify coat color‐associated molecular differences. Black‐coated sheep showed coordinated upregulation of melanogenesis and melanosome‐related genes together with pathways linked to redox balance, mitochondrial metabolism, and thermogenesis.
Putri Kusuma Astuti, Zoltán Bagi, Lilla Bodrogi, Szilvia Kusza   +3 more
wiley   +1 more source

Analysis of two not yet described member of the SLC7 family of amino acid antiporters in Drosophila melanogaster

, 2015
Analysis of two not yet described member of the SLC7 family of amino acid antiporters in Drosophila melanogaster. 16.
Galagovsky, Diego, Grosjean, Yaël
core   +2 more sources

Wheat Wild Relatives and Modern Cultivars Differ for Salt Resistance in Terms of Morpho‐Physiological Traits

Journal of Plant Nutrition and Soil Science, Volume 189, Issue 5, Page 721-734, October 2026.
Wheat wild relatives are untapped genetic resources from salinity and drought hit areas. This study presents differential comparative morphophysiological responses of these species and modern wheat cultivars under saline conditions. Salt resistant species produce more shoot and root biomass under saline conditions through salt exclusion and/or tissue ...
Muhammad Saqib, Riya Raj, Michael Frei
wiley   +1 more source

GhSCAMP13 Negatively Modulates Salt Tolerance Through GhNHX7b‐Dependent Na+ Homeostasis in Cotton

Plant Biotechnology Journal, EarlyView.
Haohong Tang, Zhaojie He, Cong Sun, Haonan Shi, Zhan Gao, Yanlong Jin, Wenting Ji, Linfu Feng, Ning Wang, Zunzhe Tian, Guanjing Hu, Jie Sun, Xianpeng Xiong   +12 more
wiley   +1 more source

First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman, Rafid Muntasir Ul Azam, Md. Sazib Hossain, Samina Momtaz, Anowara Begum, Munawar Sultana   +5 more
wiley   +1 more source

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

MedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng, Qi Qin, Fang Wang, Kaiyuan Zhang, Zhihua Li, Junlei Chang, Min Yu, Fuyou Guo   +7 more
wiley   +1 more source