Results 91 to 100 of about 263,171 (350)

Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium‐dependent, non‐D2 receptor‐dependent, manner

open access: yesPharmacology Research & Perspectives, 2021
Dopamine D2‐like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers due to their ability to cross the blood‐brain barrier.
Jillian S. Weissenrieder   +7 more
doaj   +1 more source

Late onset psychosis treatment with adjunctive medicines

open access: yesFrontiers in Psychiatry, 2023
BackgroundA number of studies have shown the feasibility of using adjunctive drugs in late onset psychosis (LOP).AimTesting hypothesis that among LOP people treated with antipsychotics and antidepressants, basing on certain clinical characteristics a ...
Irina Boksha   +6 more
doaj   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Administering LAAIs: an education and training workshop [PDF]

open access: yes, 2013
This is the second of two articles that focus on the inter-collaborative work, between education and practice, to enhance theoretical and practical delivery for mental health nurses when administrating long-acting antipsychotic injections (LAAIs).
Covill, Carl   +3 more
core   +1 more source

Linking Brain Morphometry to Psychometric Measures and Energy‐Metabolic Biomarkers in Adults With Autism Spectrum Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is associated with differences in neurodevelopment and altered metabolism, yet the interplay between brain morphometry, mitochondrial and energy metabolism biomarkers, and autistic traits in adults remains poorly understood. This study investigates the link between brain structure, psychometric measures, and both
Eleonora Esposto   +10 more
wiley   +1 more source

Quetiapine-induced priapism

open access: yesMedicine Science, 2018
Priapism is a urologic emergency characterized by a prolonged, persistent, and painful penile erection in the absence of sexual stimulation. The reports indicate that several conditions can cause priapism such as psychotropic medication.
Murat Eren Ozen   +3 more
doaj   +1 more source

Problems associated with the diagnosis and the prescribing of anti-psychotic medication in children and adolescents for psychiatric conditions, by non-psychiatric specialists [PDF]

open access: yes, 2009
Aim: The objective of this study is to assess the accuracy of the diagnosis and appropriateness of antipsychotic medication prescribed to children and adolescents referred to child guidance clinic, and how many of these remained on the said medication ...
Camilleri, Nigel   +2 more
core  

The longitudinal interplay between negative and positive symptom trajectories in patients under antipsychotic treatment: a post hoc analysis of data from a randomized, 1-year pragmatic trial [PDF]

open access: yes, 2013
BACKGROUND: Schizophrenia is a highly heterogeneous disorder with positive and negative symptoms being characteristic manifestations of the disease. While these two symptom domains are usually construed as distinct and orthogonal, little is known about ...
Ascher-Svanum, H   +6 more
core   +2 more sources

A Study to Assess the Therapeutic Effect of Enalapril on Olanzapine Induced Metabolic Syndrome in Wistar Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Metabolic Syndrome (MS) is a complex of risk factors for the development of cardiovascular complications and Type 2 Diabetes Mellitus (DM). Pharmacological management of the condition is complex, as multiple drug groups have to be used,
Avinash Arivazhahan   +3 more
doaj   +1 more source

Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice [PDF]

open access: yes, 2015
Acknowledgments We thank Luca Giordano, Giovanni Esposito and Angelo Russo for technical assistance and Dr. Livio Luongo (Second University of Naples–Italy) for critical discussions.
Avagliano, Carmen   +11 more
core   +2 more sources

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