Results 81 to 90 of about 84,866 (261)
Chlorpromazine induced priapism from a single dose: an unusual complication of antipsychotic agent
Russian Open Medical Journal, 2017 Priapism is considered as an unusual andrological emergency that requires urgent intervention. It is defined as prolonged penile erection (usually painful) for more than 4 hours not related to sexual excitation or stimulation.
Mohamed Ahmed Abd El Salam, Hisham Foaad
doaj +1 more source
Paediatric developmental safety and the ICH E11A extrapolation of safety
British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart +6 more
wiley +1 more source
Navigating the Prescription Drug Information System
Clinical Pharmacology &Therapeutics, EarlyView.Information on new prescription drugs is increasingly complex and fragmented, posing challenges for healthcare professionals, patients, and payers. Clinicians require concise, actionable guidance to support prescribing decisions, while patients seek to balance benefits and harms when making decisions aligned with their treatment goals.
Irina V. Wang +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Antipsychotics are often prescribed in the management of behaviors and psychological symptoms of dementia. While the potential harms of antipsychotic use in people with dementia have been established, little is known about the risk associated with antipsychotic drug–drug interactions (DDIs). This study aims to examine the patterns of antipsychotic DDIs
Edward C.Y. Lau +7 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez +6 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective This study examined cortical thickness and appetite‐regulating hormones—neuropeptide Y (NPY) and ghrelin—to better understand the neurobiological mechanisms underlying binge eating disorder (BED) and obesity in adolescence. We compared adolescents with BED and obesity, adolescents with obesity without BED, and healthy controls (HCs),
Serkan Turan +10 more
wiley +1 more source
Frontiers in PsychiatryBackgroundOptimal use of psychotropic medications for people living with dementia is important. By finding potentially modifiable factors, dementia care teams may find solutions to achieve the appropriate use of psychotropic drugs.ObjectiveThis study ...
Wei-Chieh Chan +5 more
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca +10 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.
Emanuele Cerulli Irelli +12 more
wiley +1 more source
Frontiers in PsychiatryIntroductionHypnotic polypharmacy and its long-term prescriptions constitute the inappropriate use of hypnotics. However, the relationship between hypnotic polypharmacy and prolonged prescriptions remains unclear.
Munehiro Komatsu +10 more
doaj +1 more source