Results 121 to 130 of about 41,988 (210)

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Altered heart rate dynamics associated with antipsychotic-induced subjective restlessness in patients with schizophrenia

, 2013
Jong-Hoon Kim,1,2 Jun-Hyung Ann,2 Jinyoung Lee,1 Mee-Hee Kim,1 Ah-Young Han1 1Department of Psychiatry, Gil Medical Center, 2Graduate School of Medicine, Gachon University, Incheon, South Korea Background: Antipsychotic-induced subjective inner ...
Han AY, Ann JH, Lee J, Kim MH, Kim JH
core  

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

The Psychometric Properties and Clinical Usefulness of the Difficulties in Emotion Regulation Scale in Forensic Settings

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objective The Difficulties in Emotion Regulation Scale (DERS) is a widely used measure of emotion dysregulation across clinical contexts. However, its psychometric properties and clinical utility have not been thoroughly examined in forensic populations.
Adam Meddeb, Märta Wallinius, Johan Berlin, Natalie Laporte, Malin Hildebrand Karlén, Claudia Mazzeschi, Elisa Delvecchio, Patrizia Velotti, Carlo Garofalo   +8 more
wiley   +1 more source

Predictors of antipsychotic monotherapy with olanzapine during a 1-year naturalistic study of schizophrenia patients in Japan

, 2012
Wenyu Ye1, Haya Ascher-Svanum2, Jennifer A Flynn3, Yuka Tanji3, Michihiro Takahashi3,41Lilly Suzhou Pharmaceutical Co, Shanghai, People's Republic of China; 2Eli Lilly and Company, Indianapolis, IN, USA; 3Lilly Research Laboratories Japan, Eli ...
Tanji Y, Ascher-Svanum H, Ye W, Flynn JA, Takahashi M   +4 more
core  

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz, Leyre Gambra, Samuele Cortese, Pablo Lizoain, Diana Rodriguez‐Romero, Ursula Paiva, Carmen Gándara, Sara Magallón, Gonzalo Arrondo   +8 more
wiley   +1 more source

Predictors and moderators of problem‐focused social skills training versus resource activation for children with disruptive behavior problems

JCPP Advances, EarlyView.
Abstract Background Not all children benefit equally from evidence‐based treatments for disruptive behavior disorders (DBD). In a previous randomized controlled trial (RCT), computer‐facilitated social skills training (ScouT) demonstrated superior efficacy over solution‐focused, resource‐oriented treatment (STARK) in reducing parent‐rated peer‐related ...
Leonie Hofmann, Christina Dose, Manfred Döpfner, Anja Görtz‐Dorten   +3 more
wiley   +1 more source

Racial and ethnic differences in hospital‐based low‐value pediatric care

Journal of Hospital Medicine, EarlyView.
Abstract Background Low‐value care (LVC), or care in which potential risk outweighs perceived benefits, continues to impact pediatric populations. While pediatric healthcare delivery is known to vary across racial and ethnic groups, little is known about the relationship between race and ethnicity and LVC.
Elisha McCoy, Megan E. Collins, Jillian M. Cotter, Natalie Grills, Matt Hall, Jessica Markham, Matthew J. Molloy, Michelle Polich, Michael J. Steiner, John R. Stephens, Michael J. Tchou, Ronald Teufel II, Irma Ugalde, Andrew Yu, Samantha A. House   +14 more
wiley   +1 more source

Addressing limitations in current measurement practices of trauma assessment in minoritized populations

Journal of Traumatic Stress, EarlyView.
Abstract Standardized trauma assessment frameworks often fail to account for the unique experiences and symptom presentations of minoritized populations, including Black, Indigenous, and people of color (BIPOC) and sexual and gender minority (SGM) individuals, leading to methodological inequity.
Krithika Prakash, Selime R. Salim, Colin T. Mahoney, Phillip W. Schnarrs, Antonio A. Morgan‐López   +4 more
wiley   +1 more source

Structurally competent care for families facing the continuous traumatic stress of community violence and systemic racism

Journal of Traumatic Stress, EarlyView.
Abstract In racially and economically segregated communities, structural violence and chronic adversity perpetuate the risk for community violence and related trauma exposure. Despite widespread awareness of community violence, urban youth of color are among those least likely to have access to services that promote trauma recovery. When these youth do
Bradley C. Stolbach, Seeba Anam, Keyona Allen, Emma‐Lorraine Baaba Bart‐Plange, Royce Lee, Aashana Daru, Angel Boulware, Sonya Mathies Dinizulu   +7 more
wiley   +1 more source