Results 41 to 50 of about 181,112 (317)

Antipsychotic Treatment Failure: A Systematic Review on Risk Factors and Interventions for Treatment Adherence in Psychosis

open access: yesFrontiers in Neuroscience, 2020
Objective: Antipsychotic medication non-adherence has detrimental effects on patients' clinical outcome. It is unclear which risk factors affect adherence most and which interventions are effective at improving adherence to antipsychotic medication.
Kawtar El Abdellati   +5 more
doaj   +1 more source

Effectiveness of antipsychotics in schizophrenia with comorbid substance use disorder

open access: yesEuropean Psychiatry, 2021
Introduction Schizophrenia is highly comorbid with substance use disorders (SUD), which may negatively impact the course of illness. However, large studies exploring the best lines of treatment for this combination are lacking.
M. Lähteenvuo   +6 more
doaj   +1 more source

Causal Discovery on the Effect of Antipsychotic Drugs on Delirium Patients in the ICU using Large EHR Dataset [PDF]

open access: yesarXiv, 2022
Delirium occurs in about 80% cases in the Intensive Care Unit (ICU) and is associated with a longer hospital stay, increased mortality and other related issues. Delirium does not have any biomarker-based diagnosis and is commonly treated with antipsychotic drugs (APD).
arxiv  

Association Study of the Complement Component C4 Gene in Tardive Dyskinesia

open access: yesFrontiers in Pharmacology, 2019
Tardive dyskinesia (TD) is a movement disorder that may develop in schizophrenia patients being treated long-term with antipsychotic medication. TD interferes with voluntary movements and leads to stigma, and can be associated with treatment non ...
Clement C. Zai   +30 more
doaj   +1 more source

Management of antipsychotic-related sexual dysfunction

open access: yesEuropean Psychiatry, 2022
Introduction Sexual dysfunction (SD) can often be a side-effect of treatment with antipsychotics (APS). It often jeopardizes long-term adherence to treatment, while deeply affecting the patient’s quality of life.
C. Rodrigues
doaj   +1 more source

20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia.

open access: yesAmerican Journal of Psychiatry, 2018
OBJECTIVE It is generally believed that after the first episode of schizophrenia, the risk of relapse decreases with time in patients who are stabilized.
J. Tiihonen, A. Tanskanen, H. Taipale
semanticscholar   +1 more source

MicroRNA binding site variation is enriched in psychiatric disorders

open access: yesHuman Mutation, Volume 43, Issue 12, Page 2153-2169, December 2022., 2022
Abstract Psychiatric disorders have a polygenic architecture, often associated with dozens or hundreds of independent genomic loci. Most associated loci impact noncoding regions of the genome, suggesting that the majority of disease heritability originates from the disruption of regulatory sequences.
Michael P. Geaghan   +2 more
wiley   +1 more source

Improving metabolic and cardiovascular health at an Early Psychosis Intervention program in Vancouver, Canada

open access: yesFrontiers in Psychiatry, 2014
Psychotic disorders most commonly appear during the late teenage years and early adulthood. A focused and rapid clinical response by an integrated health team can help to improve the quality of life of the patient, leading to a better long-term prognosis.
Diane H. Fredrikson   +7 more
doaj   +1 more source

Automated Interlaboratory Comparison of Therapeutic Drug Monitoring Data and Its Use for Evaluation of Published Therapeutic Reference Ranges

open access: yesPharmaceutics, 2023
Therapeutic drug monitoring is a tool for optimising the pharmacological treatment of diseases where the therapeutic effect is difficult to measure or monitor.
Jens Borggaard Larsen   +4 more
doaj   +1 more source

Hormonal alterations due to antipsychotic-related hyperprolactinemia

open access: yesEuropean Psychiatry, 2022
Introduction The use of antipsychotics (APS) is essential. Despite their great efficacy, some of them are associated with an increase in prolactin levels that can lead to hormonal changes needing to be identified and managed [1,2,3].
A.L. Montejo   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy