Results 31 to 40 of about 84,866 (261)

Early improvements of individual symptoms as a predictor of treatment response to asenapine in patients with schizophrenia

Neuropsychopharmacology Reports, 2020
Aim It is well accepted that early improvement with antipsychotics predicts subsequent response in patients with schizophrenia. However, no study has examined the contribution of individual symptoms rather than overall symptom severity as the predictors.
Kamiyu Ogyu, Yoshihiro Noda, Kazunari Yoshida, Shin Kurose, Fumi Masuda, Yu Mimura, Hana Nishida, Eric Plitman, Ryosuke Tarumi, Sakiko Tsugawa, Masataka Wada, Takahiro Miyazaki, Hiroyuki Uchida, Ariel Graff‐Guerrero, Masaru Mimura, Shinichiro Nakajima   +15 more
doaj   +1 more source

Pd/C‐Catalyzed Hydrogenation of CF3‐, CF2H‐, and CF2CO2Et‐containing Pyridines: A Robust Method for Highly Functionalized containing Piperidines

Angewandte Chemie, EarlyView.
A robust and efficient method to access diversely functionalized fluorinated piperidines was developed. The approach features the hydrogenation of polysubstituted pyridines bearing CF3, CF2H, and CF2CO2Et substituents using an inexpensive, readily available heterogeneous Pd/C catalyst under air‐ and moisture‐tolerant conditions, offering an appealing ...
Thibaud Charvillat, Patrick Bernardelli, Marc Daumas, Xavier Pannecoucke, Vincent Ferey, Hassan Oulyadi, Muriel Sebban, Tatiana Besset   +7 more
wiley   +2 more sources

Successful high dose antipsychotic treatment with cariprazine in patients on the schizophrenia spectrum: Real-world evidence from a Spanish hospital setting

Frontiers in Psychiatry, 2023
Real-world evidence fills in an important gap by providing data on the effectiveness and tolerability of new medications in everyday patients. In this data collection form a Spanish hospital, the effectiveness and tolerability of cariprazine were ...
Lluis Niell Galmes, Elmars Rancans
doaj   +1 more source

Perspectives on Precision Psychiatry Using Antipsychotics in the Management of Bipolar Disorder

Brain Sciences
Background/Objectives: Precision medicine is not just hype. Instead, it represents a high bar for developing more effective, safer, and better-tolerated therapies in medicine, without exception in psychiatry, including bipolar disorder (BD). A burgeoning
Michele Fornaro, Alessandro Miola, Domenico De Berardis, Alessio Squassina, Mirko Manchia, Marco Solmi   +5 more
doaj   +1 more source

Pulmonary embolism in a patient with neuroleptic malignant syndrome

Hematology Reports, 2018
Venous thromboembolism is one of the complications in patients prescribed antipsychotic medications. Neuroleptic malignant syndrome (NMS) is a rare side effect of antipsychotic medications in this population.
Mosaad Almegren
doaj   +1 more source

Antipsychotic-Related Risks of Type 2 Diabetes Mellitus in Enrollees With Schizophrenia in the National Basic Public Health Service Program in Hunan Province, China

Frontiers in Psychiatry, 2022
BackgroundAntipsychotics contribute to the development of type 2 diabetes mellitus (T2DM) in individuals with schizophrenia. However, the extent of the relationship between antipsychotic use and T2DM varies in different settings, and the magnitude of the
Feiyun Ouyang, Jun He, Xunjie Cheng, Wei Zhou, Shuiyuan Xiao, Junqun Fang   +5 more
doaj   +1 more source

Safety and Effectiveness of Lurasidone in Patients with Schizophrenia: A 12-Week, Open-Label Extension Study

Neuropsychiatric Disease and Treatment, 2021
Masaomi Iyo,1 Jun Ishigooka,2 Masatoshi Nakamura,3 Reiko Sakaguchi,4 Keisuke Okamoto,5 Yongcai Mao,6 Joyce Tsai,7 Alison Fitzgerald,8 Kentaro Takai,9 Teruhiko Higuchi10,11 1Department of Psychiatry, Graduate School of Medicine, Chiba University, Chiba ...
Iyo M, Ishigooka J, Nakamura M, Sakaguchi R, Okamoto K, Mao Y, Tsai J, Fitzgerald A, Takai K, Higuchi T   +9 more
doaj  

Antipsychotic combinations for schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2017
Many people with schizophrenia do not achieve a satisfactory treatment response with their initial antipsychotic drug treatment. Sometimes a second antipsychotic, in combination with the first, is used in these situations.To examine whether:1. treatment with antipsychotic combinations is effective for schizophrenia; and2.
Javier, Ortiz-Orendain, Santiago, Castiello-de Obeso, Luis Enrique, Colunga-Lozano, Yue, Hu, Nicola, Maayan, Clive E, Adams   +5 more
openaire   +4 more sources

Effect of Metformin on Antipsychotic-Induced Metabolic Dysfunction: The Potential Role of Gut-Brain Axis

Frontiers in Pharmacology, 2019
Antipsychotics are the first-line medications prescribed for patients with schizophrenia or other mental disorders. Cumulative evidence has revealed that metabolic dysfunctions frequently occur in patients receiving antipsychotics, especially second ...
Chao Luo, Chao Luo, Chao Luo, Xu Wang, Xu Wang, Hanxue Huang, Hanxue Huang, Xiaoyuan Mao, Xiaoyuan Mao, Honghao Zhou, Honghao Zhou, Honghao Zhou, Zhaoqian Liu, Zhaoqian Liu, Zhaoqian Liu   +14 more
doaj   +1 more source

The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Psychosis in Alzheimer's disease (AD) is associated with grave clinical consequences including a precipitous cognitive decline and a hastened demise.
Heidy Jimenez, Leslie Adrien, Adam Wolin, John Eun, Eric H. Chang, Ethan S. Burstein, Jesus Gomar, Peter Davies, Jeremy Koppel   +8 more
doaj   +1 more source