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Pharmacogenetics of Antipsychotics [PDF]
Objective: During the past decades, increasing efforts have been invested in studies to unravel the influence of genetic factors on antipsychotic (AP) dosage, treatment response, and occurrence of adverse effects.
Eva J, Brandl +2 more
openaire +2 more sources
Cannabis and schizophrenia [PDF]
BACKGROUND Schizophrenia is a mental illness causing disordered beliefs, ideas and sensations. Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear
Gillies, Donna +6 more
core +1 more source
Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]
Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S +3 more
core +3 more sources
Antipsychotics and Amotivation [PDF]
Antipsychotic drugs are thought to produce secondary negative symptoms, which can also exacerbate primary negative symptoms. In the present study, we examined whether motivational deficits in particular were related to antipsychotic treatment in patients with schizophrenia in a dose-dependent manner.
Gagan, Fervaha +6 more
openaire +2 more sources
Key Clinical Message In some patients, neuroleptic malignant syndrome is accompanied significant high levels of erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP).
Forouzan Elyasi +5 more
doaj +1 more source
Antipsychotic Response in the First Week Predicts Later Efficacy [PDF]
Background and Aims: Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response.
Andrisano, Costanza +7 more
core +1 more source
Adjunctive antidepressive pharmacotherapy in schizophrenia patients
Depressive symptoms during long-term course of schizophrenia constitute an important and frequent clinical problem. They may occur either as stand-alone major depressive episodes (MDEs) or as part of the schizophrenic negative syndrome.
M. Zink
doaj +1 more source
Management of common adverse effects of antipsychotic medications
The benefits of antipsychotic medications are sometimes obscured by their adverse effects. These effects range from relatively minor tolerability issues (e.g., mild sedation or dry mouth) to very unpleasant (e.g., constipation, akathisia, sexual ...
T. Stroup, Neil A. Gray
semanticscholar +1 more source
Physicians who treat patients with schizophrenia frequently encounter complex clinical situations not fully addressed by published treatment guidelines. Some of these situations lead to antipsychotic polypharmacy, often prescribed when clinical and social obstacles prevent access to clozapine and patients have had suboptimal responses to nonclozapine ...
Adriana, Foster, Jordanne, King
openaire +3 more sources
Comparison of droperidol and haloperidol for acute agitation in the emergency department: A retrospective cohort study [PDF]
Introduction To compare the effectiveness of droperidol and haloperidol for acute agitation in the emergency department. Methods Data from electronic health records were collected from January 1, 2022, to August 25, 2023, across 6 emergency departments ...
Francesca DiGuglielmo, PharmD +4 more
doaj +1 more source

