Chemistry &Biodiversity, EarlyView.ABSTRACT Anxiety is a multidimensional behavioral disorder widely studied in neuroscience due to the involvement of specific neural circuits. Although benzodiazepines are commonly used, their side effects drive the search for new therapeutic alternatives.
Nádia Aguiar Portela Pinheiro +11 more
wiley +1 more source
Inhibition of the oncogenic channel Kv10.1 by the antipsychotic drug penfluridol
Frontiers in PharmacologyDrug repurposing is an increasingly recognized strategy in pharmaceutical development that focuses on identifying new therapeutic uses for already approved drugs, as an alternative to the time-consuming and costly process of developing new molecular ...
Paulina León-Sánchez +7 more
doaj +1 more source
Neurocognitive Correlates of Treatment Response in Children with Tourette\u27s Disorder [PDF]
, 2018 This paper examined neurocognitive functioning and its relationship to behavior treatment response among youth with Tourette\u27s Disorder (TD) in a large randomized controlled trial.
Chang, Susanna W. +8 more
core +2 more sources
Association Between D‐amino Acids in Natto (fermented soybeans) and Kidney Dysfunction
ChemFoodChem, EarlyView.XX XX ABSTRACT In this study, we examined clinical and cohort data to explore the potential renoprotective effects of natto (fermented soybeans) consumption and its relationship with D‐amino acids. In a clinical study, ten healthy adults consumed one 40‐g pack of natto three times in a single day, and plasma and urine samples were collected 1 h and 24 ...
Yusuke Nakade +19 more
wiley +1 more source
Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]
, 2006 It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko +3 more
core +1 more source
The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes
Clinical Pharmacology &Therapeutics, EarlyView.Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali +4 more
wiley +1 more source
Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]
, 2017 Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Chiriță, Cornel +4 more
core +4 more sources
Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations
Clinical Pharmacology &Therapeutics, EarlyView.Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar +9 more
wiley +1 more source
Impact of antipsychotics on the sexuality of patients diagnosed with schizophrenia [PDF]
, 2023 Fares Jaballah
openalex +1 more source
Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]
, 2019 BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A +7 more
core +1 more source