Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database. [PDF]
Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with ...
Brunner, Elizabeth+8 more
core +3 more sources
Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]
Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S+3 more
core +3 more sources
Symptomatic Resolution Among Chinese Patients With Schizophrenia and Associated Factors
The remission and resolution criteria for schizophrenia were defined by the Remission in Schizophrenia Working Group in 2005, using eight core items of the positive and negative symptoms scale for schizophrenia.
Cheng-Ta Li+7 more
doaj +1 more source
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina+3 more
doaj +1 more source
Different types of akathisia: clinical analysis on three cases
Objective To explore the clinical presentations, probable pathogenesis and therapy of different types of akathisia. Methods and Results There were 3 cases of akathisia in this report. The diagnosis of Case 1 was acute akathisia, drug-induced parkinsonism,
Lei WANG+4 more
doaj +1 more source
Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment. [PDF]
Complex interactions between the immune system and the brain might have important aetiological and therapeutic implications for neuropsychiatric brain disorders.
Cousins, Lesley+5 more
core +2 more sources
Myocarditis in patients on long-term antipsychotics –mechanism, management and recent updates
Objective: Clozapine is the first atypical antipsychotic drug and was frequently cited as the most effective antipsychotic for treatment-resistant schizophrenia, but it is associated with a concert of significant cardiotoxic side effects.
Patterson Daniel+6 more
doaj
Quetiapine-induced Priapism Requiring Frequent Emergency Admissions: A Case Report
Priapism, a rare but well-known adverse reaction of first and second generation anti-psychotics, has been hypothesized to be associated with blockade of alpha 1 receptors. However, genetic abnormalities or heritability of affected cytochrome P450 alleles
Jon C. Jackson, Chasity L. Torrence
doaj +1 more source
Neuropsychological assessment and treatment possibilities of cognitive deficit in schizophrenic patients [PDF]
nema
Totić-Poznanović Sanja+4 more
doaj +1 more source
Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F+7 more
core +1 more source