Results 31 to 40 of about 3,362,668 (327)

Benefits of Community-based Treatment for Patients with Schizophrenia: Based on Long-acting Injectable Antipsychotic Agents [PDF]

Zhongguo quanke yixue
Schizophrenia could affect the social and occupational functions of patients in the long term. Community-based mental health services and management models promote mental health by improving accessibility, acceptability, affordability, practicality and ...
Schizophrenia Coordination Group, Chinese Society of Psychiatry, Chinese Society of General Practice, LI Qian, SI Tianmei
doaj   +1 more source

Neuropsychological assessment and treatment possibilities of cognitive deficit in schizophrenic patients [PDF]

Vojnosanitetski Pregled, 2012
nema
Totić-Poznanović Sanja, Pavlović Dragan M., Đorđević Jelena R., Pavlović Aleksandra M., Marinković Dragan   +4 more
doaj   +1 more source

Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT2A Antagonist

Journal of Chemistry, 2013
Schizophrenia is a mental disorder manifested largely by disintegration of thought processes and emotional responsiveness. Given the therapeutic and toxic limitations of clinically available drugs, it is clear that there is still a need for the ...
Mahantesh Namdev Jadhav, Ganesh Rajendra Kokil, Shilpa Sudhakar Harak, Sanjay Baburao Wagh   +3 more
doaj   +1 more source

QT interval prolongation related to psychoactive drug treatment: a comparison of monotherapy versus polytherapy

Annals of General Psychiatry, 2005
Background Several antipsychotic agents are known to prolong the QT interval in a dose dependent manner. Corrected QT interval (QTc) exceeding a threshold value of 450 ms may be associated with an increased risk of life threatening arrhythmias ...
Piccinelli Marco, Bonzano Alberto, Jogia Jigar RS, Caverzasi Eduardo, Montomoli Cristina, Brambilla Paolo, Vicentini Alessandro, Sala Michela, Barale Francesco, De Ferrari Gaetano M   +9 more
doaj   +1 more source

Assessment of adherence to treatment with injectable extended-release antipsychotics within a pharmacotherapeutic follow-up program [PDF]

Farmacia Hospitalaria, 2019
Objective: To describe an injectable extended-release antipsychotic pharmacotherapeutic follow-up program and to assess adherence among patients included in the program.
Carmen Gallastegui, Hadriana Fernández-Vega, Guadalupe Piñeiro, Isabel Rey-Gómez-Serranillos, José M. Olivares, Elena de las Heras-Liñero   +5 more
doaj   +1 more source

Neuroleptic malignant syndrome

Journal of Family Medicine and Primary Care, 2016
Neuroleptic malignant syndrome (NMS) is a life-threatening emergency that is often seen as a complication of antipsychotic agents. It is characterized by a tetrad of motor, behavioral, autonomic, and laboratory abnormalities.
Bino Rajamani, Yashwant Kumar, Sajitha M.F. Rahman   +2 more
doaj   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Existing and emerging pharmacological approaches to the treatment of mania: A critical overview

Translational Psychiatry, 2022
Manic episodes are a defining, frequent and dramatically disabling occurrence in the course of Bipolar Disorder type I. Current pharmacotherapy of mania lists a good number of agents, but differences in efficacy and safety profiles among these agents ...
Giulio Sparacino, Norma Verdolini, Eduard Vieta, Isabella Pacchiarotti   +3 more
doaj   +1 more source

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård, Caroline Theilgaard Thorarinsson, Jan Nielsen, Mette Louise Andersen, Jens Kjeldsen, Torben Knudsen, Rahul S. Dalal   +6 more
wiley   +1 more source

Clinical pharmacology consultations and their implementation in clinical decision making

British Journal of Clinical Pharmacology, EarlyView.
Aims One of the key roles of clinical pharmacologists is to work as consultants for other medical specialties. We wanted to investigate the characteristics of clinical pharmacology consultations, compare the types of consultations from different specialties, and evaluate how well the recommendations given were followed.
Mirjam Kauppila, Janne T. Backman, Outi Lapatto‐Reiniluoto   +2 more
wiley   +1 more source