Results 51 to 60 of about 169 (158)

A Realist Evaluation of a Rapid Response System for Mental State Deterioration in Acute Hospital Settings

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Background Patient mental state deterioration presents significant challenges in acute hospital settings, affecting outcomes, increasing reliance on restrictive interventions, and placing additional strain on healthcare staff. Despite its prevalence, consensus on best practice remains limited.
Tendayi Bruce Dziruni   +3 more
wiley   +1 more source

Annual Research Review: Psychosis in children and adolescents – a call to action: a commentary on Kelleher (2025)

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 588-591, April 2025.
The spectrum of psychosis is highly relevant to child and adolescent mental health. Psychotic symptoms are common in children and adolescents. The onset of psychotic disorders is often preceded by neurodevelopmental problems in early childhood, and some 13% of adolescents attending specialist mental health services will later be diagnosed with a ...
James G. Scott
wiley   +1 more source

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

open access: yesJournal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li   +7 more
wiley   +1 more source

Substitution Patterns After Discontinuation of CNS‐Active Medications in Older Adults in Primary Care

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray   +6 more
wiley   +1 more source

Anticholinergic Medication Use in Veterans Affairs Long‐Term Care Residents: Clinical Patterns and Opportunities for Deprescribing

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Anticholinergic exposure is common in nursing homes; however, the true burden may be underestimated, particularly due to over‐the‐counter agents such as first‐generation antihistamines that are not consistently captured in prior claims‐based studies.
Cellas A. Hayes   +5 more
wiley   +1 more source

Hospice Care in the Era of AI: Hospices' Views on Data‐Driven Tools to Support Live Discharge Decisions

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Live discharge occurs for 20% of hospice enrollees, resulting in loss of support and disruptive care transitions, with higher risk for patients with Alzheimer's disease and related dementias (ADRD). Little is understood about how data‐driven clinical decision support tools (e.g., predictive algorithms) might support decision making ...
Elizabeth A. Luth   +4 more
wiley   +1 more source

Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Psychotropic use and psychotropic polypharmacy are common in people with intellectual disabilities, but representative population‐based studies on this topic are scarce. We evaluated the prevalence of psychotropic use and psychotropic polypharmacy in a Finnish nationwide cohort of people with intellectual disabilities aged 0–97 ...
Ville Virtanen   +6 more
wiley   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

open access: yesJournal of Oral Rehabilitation, EarlyView.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel   +3 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may influence subjective sleepiness and objective alertness.
Anice Borjon   +13 more
wiley   +1 more source

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