Serum levels of antipsychotic agents.
Fasting serum levels of antipsychotic agents, given in nM, after 2 or 8 weeks of treatment, respectively.
Vidar Martin Steen (116127) +6 more
core +1 more source
Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication:an exploratory trial [PDF]
Background. Although antipsychotic medication is the first line of treatment for schizophrenia, many service users choose to refuse or discontinue their harmacological treatment.
Hutton, P. +49 more
core +1 more source
Assessment of adherence to treatment with injectable extended-release antipsychotics within a pharmacotherapeutic follow-up program [PDF]
Objective: To describe an injectable extended-release antipsychotic pharmacotherapeutic follow-up program and to assess adherence among patients included in the program.
Carmen Gallastegui +5 more
doaj +1 more source
Neuroleptic malignant syndrome
Neuroleptic malignant syndrome (NMS) is a life-threatening emergency that is often seen as a complication of antipsychotic agents. It is characterized by a tetrad of motor, behavioral, autonomic, and laboratory abnormalities.
Bino Rajamani +2 more
doaj +1 more source
Existing and emerging pharmacological approaches to the treatment of mania: A critical overview
Manic episodes are a defining, frequent and dramatically disabling occurrence in the course of Bipolar Disorder type I. Current pharmacotherapy of mania lists a good number of agents, but differences in efficacy and safety profiles among these agents ...
Giulio Sparacino +3 more
doaj +1 more source
Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database. [PDF]
Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with ...
Van Staa, Tjeerd; id_orcid +8 more
core +1 more source
CLOZAPINE AND HALOPERIDOL INCREASE THE EXPRESSION OF PED/PEA-15: A PUTATIVE NOVEL MECHANISM FOR ANTIPSYCHOTIC-RELATED DIABETES [PDF]
Schizophrenia is a serious disorder that affects 1% of the population in the United States and Europe, and is associated with a significant reduction in life expectancy that approaches 20% compared with that of the general population.
Panariello, Fabio
core +1 more source
Antipsychotic treatment patterns and cardiometabolic medicine use: current real-world evidence
Aims Off-label use of antipsychotics, often at low doses, is increasing. Exploring the link between individual antipsychotic treatment patterns, including low-dose continuous use, and cardiometabolic health is crucial to prevent long-term morbidity and ...
Ramya Padmavathy Radha Krishnan +3 more
doaj +1 more source
Do Atypical Antipsychotic Agents Trigger Autoimmune Diabetes?
Atypical or second-generation antipsychotic agents, such as aripiprazole and olanzapine, are increasingly used in the management of schizophrenia and bipolar disorders in children.
Soyka, Leslie A. +4 more
core +1 more source
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors [PDF]
The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5-HT6) and rat 5-hydroxytryptamine-7 (5-HT7) receptors in transiently expressed COS-7 cells (5-HT7) or stably transfected HEK ...
Sibley, David R. +7 more
core +1 more source

