Results 61 to 70 of about 169 (158)
Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai +5 more
wiley +1 more source
Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung +4 more
wiley +1 more source
QTc Interval Prolongation and Associated Drug Therapy in Hospitalized Older Adults
Journal of the American Geriatrics Society, EarlyView.
Francesco Fantin +7 more
wiley +1 more source
Adverse outcomes between VMAT2 and anticholinergics in tardive dyskinesia: A target trial emulation
Aim Vesicular monoamine transporter 2 (VMAT2) inhibitors have been approved for the treatment of tardive dyskinesia (TD), whereas anticholinergic agents are still widely used for this condition. This study aimed to compare the risk of major clinical adverse outcomes among patients with TD treated with VMAT2 inhibitors versus anticholinergic agents ...
Tien‐Wei Hsu +13 more
wiley +1 more source
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui +11 more
wiley +1 more source
Circular inference in visual cortical hierarchies in schizophrenia
Aim In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top‐down priors and bottom‐up likelihoods are represented across the hierarchy of visual cortices. To identify these processes within cortical hierarchies, the circular inference model offers a framework to account for the biased ...
Shuhei Hara +7 more
wiley +1 more source
Of mice and men—The emerging oral–gut–brain axis of health and disease
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila +1 more
wiley +1 more source
Psychotropic medication and the fetal brain
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley +1 more source
Objective This study evaluated whether intramuscular (IM) ketamine is non‐inferior to intranasal (IN) esketamine for treatment‐resistant depression (TRD) and assessed differences in safety and healthcare costs. Methods In a retrospective, observational sequential cohort at the VA San Diego, 179 Veterans with TRD received eight treatments of either IN ...
Kush V. Bhatt +12 more
wiley +1 more source
ABSTRACT Objectives Basic self‐disturbance is an abnormality in subjective self‐experience and a core feature of schizophrenia. The Inventory of Psychotic‐Like Anomalous Self‐Experiences (IPASE) is a self‐report measure designed to assess basic self‐disturbance. Despite its clinical utility, a Japanese version has not yet been established.
Dan Nakamura +12 more
wiley +1 more source

