Results 11 to 20 of about 222,704 (323)

Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis.

The Lancet, 2022
BACKGROUND Schizophrenia is a common, severe, and usually chronic disorder. Maintenance treatment with antipsychotic drugs can prevent relapse but also causes side-effects.
J. Schneider-Thoma, K. Chalkou, C. Dörries, I. Bighelli, A. Ceraso, M. Huhn, S. Siafis, John M. Davis, A. Cipriani, T. Furukawa, G. Salanti, S. Leucht   +11 more
semanticscholar   +1 more source

Pharmacokinetic Characteristics of Long-Acting Injectable Antipsychotics for Schizophrenia: An Overview

CNS Drugs, 2021
The availability of long-acting injectable (LAI) antipsychotics for the treatment of schizophrenia provides clinicians with options that deliver continuous drug exposure and may improve adherence compared with daily oral antipsychotics.
C. Correll, Edward Kim, J. K. Sliwa, Wayne Hamm, S. Gopal, M. Mathews, Raja Venkatasubramanian, Stephen R Saklad   +7 more
semanticscholar   +1 more source

Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis

Lancet psychiatry, 2020
Summary Background Antipsychotic treatment is associated with metabolic disturbance. However, the degree to which metabolic alterations occur in treatment with different antipsychotics is unclear.
T. Pillinger, R. McCutcheon, L. Vano, Y. Mizuno, A. Arumuham, Guy Hindley, K. Beck, S. Natesan, O. Efthimiou, A. Cipriani, O. Howes   +10 more
semanticscholar   +1 more source

Safety of 80 antidepressants, antipsychotics, anti‐attention‐deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta‐review of 78 adverse effects

World Psychiatry, 2020
Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental disorders in this age group and are used not infrequently off‐label.
M. Solmi, M. Fornaro, E. Ostinelli, Caroline Zangani, Giovanni Croatto, Francesco Monaco, D. Krinitski, P. Fusar-Poli, C. Correll   +8 more
semanticscholar   +1 more source

Antipsychotic Polypharmacy

Focus, 2020
Physicians who treat patients with schizophrenia frequently encounter complex clinical situations not fully addressed by published treatment guidelines. Some of these situations lead to antipsychotic polypharmacy, often prescribed when clinical and social obstacles prevent access to clozapine and patients have had suboptimal responses to nonclozapine ...
Adriana, Foster, Jordanne, King
openaire   +3 more sources

Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]

, 2002
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph, Grunze, Heinz, Marcuse, Alain, Schaerer, Lars O., Walden, Jörg   +4 more
core   +1 more source

Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis

The Lancet, 2019
Summary Background Schizophrenia is one of the most common, burdensome, and costly psychiatric disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is controversy about which agent should be used.
M. Huhn, A. Nikolakopoulou, J. Schneider-Thoma, M. Krause, M. Samara, N. Peter, Thomas Arndt, Lio Bäckers, Philipp H Rothe, A. Cipriani, John M. Davis, G. Salanti, S. Leucht   +12 more
semanticscholar   +1 more source

Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects

BMC Psychiatry, 2009
Background Although much progress has been made on antipsychotic drug development, precise mechanisms behind the action of typical and atypical antipsychotics are poorly understood.
Song Jonathan, Llenos Ida C, Weis Serge, Higgs Brandon W, Choi Kwang H, Dulay Jeannette R, Yolken Robert H, Webster Maree J   +7 more
doaj   +1 more source

Hyperprolactinemia as a side effect of using antipsychotics In Schizophrenic Patients

Jurnal Psikiatri Surabaya, 2023
Introductions: Antipsychotics are still the mainstay of schizophrenia management. Antipsychotics are antagonistic to postsynaptic dopamine receptors in the brain.
Syaiful Anwar, Khairina
doaj   +1 more source

Quality of life in Romanian patients with schizophrenia based on gender, type of schizophrenia, therapeutic approach, and family history [PDF]

, 2018
The low quality of life of patients with schizophrenia has been extensively discussed and investigated. Various aspects from gender, socio-demographic profile, and/or type of neuroleptic treatment have been taken into account in describing this condition.
Alexinschi, Ovidiu Eugen, Brîncuș, Călin, Giurgiuca, Ana, Matei, Valentin Petre, Rosca, Elena Alina   +4 more
core   +3 more sources