Results 51 to 60 of about 243,764 (341)

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

open access: yesAdvanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien   +4 more
wiley   +1 more source

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

open access: yes, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
core  

Effects of intervention with the SAFE strategy on trachoma across Ethiopia.

open access: yes, 2011
BACKGROUND/AIMS: The impact of the SAFE strategy (surgery, antibiotics, face washing, environmental hygiene), recommended to eliminate blinding trachoma, is not well explored.
Patel, D   +3 more
core   +1 more source

Asenapine versus other atycipal antipsychotics for schizoaffective disorder Case study

open access: yesEuropean Psychiatry
Introduction Antipsychotics are psyschotropic medications that are indicated for the treatment of physchosis and mood disorders. Due to minimal side effects and their efficacy (affecting many receptors) compared to standard antipsychotics, today ...
E. Shaska
doaj   +1 more source

Cost variability of antipsychotics according to pharmaceutical establishments in Lima, Peru

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2020
The objectives of the study were to determine the cost variability of antipsychotics in public (hospitals) and private pharmaceutical establishments (pharmacies and clinics), calculate the cost variability of antipsychotics between establishments and ...
Ruben Valle
doaj   +1 more source

Antipsychotics-Induced Changes in Synaptic Architecture and Functional Connectivity: Translational Implications for Treatment Response and Resistance

open access: yesBiomedicines, 2022
Schizophrenia is a severe mental illness characterized by alterations in processes that regulate both synaptic plasticity and functional connectivity between brain regions. Antipsychotics are the cornerstone of schizophrenia pharmacological treatment and,
Andrea de Bartolomeis   +6 more
doaj   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti   +13 more
wiley   +1 more source

A Cross-Sectional Study Comparing the Frequency of Drug Interactions After Adding Simeprevir- or Sofosbuvir-Containing Therapy to Medication Profiles of Hepatitis C Monoinfected Patients. [PDF]

open access: yes, 2015
INTRODUCTION:This study compares the expected occurrence of contraindicated drug-drug interactions (XDDIs) when simeprevir (SIM)- or sofosbuvir (SOF)-containing therapy is added to medication profiles of patients with hepatitis C (HCV) monoinfection to ...
Bliss, Steven   +6 more
core   +1 more source

Tackling myths of common prescribing patterns in schizophrenia amongst Egyptian psychiatrists

open access: yesMiddle East Current Psychiatry, 2020
Background There is limited data related to how psychiatrists actually choose amongst different medications, especially in Egypt. Our aim was to survey a sample of psychiatrists regarding common patterns of antipsychotic prescribing practices and review ...
Samir Abolmagd   +3 more
doaj   +1 more source

CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity

open access: yesSignal Transduction and Targeted Therapy, 2022
Long-term use of antipsychotics is a common cause of myocardial injury and even sudden cardiac deaths that often lead to drug withdrawn or discontinuation. Mechanisms underlying antipsychotics cardiotoxicity remain largely unknown.
Liliang Li   +15 more
doaj   +1 more source

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