Results 171 to 180 of about 46,160 (296)

Low‐Molecular‐Weight Heparin for Adult ICU Patients Who Require Thromboprophylaxis: Protocol for the INCEPT‐Thromboprophylaxis Platform Trial Domain

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Low‐molecular‐weight heparin (LMWH) is recommended for thromboprophylaxis in adult intensive care unit (ICU) patients. Despite its widespread use, there is insufficient evidence on the optimal dose, and there appears to be practice variation.
Ruben Eck   +10 more
wiley   +1 more source

Managing schizophrenia with affective, sexual, metabolic and substance-use comorbidities: pharmacological considerations from an expert consensus. [PDF]

open access: yesAnn Gen Psychiatry
Vieta E   +9 more
europepmc   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö   +8 more
wiley   +1 more source

Subchronic Exposure to Aripiprazole Subtly Impacts on Rodents' Sperm Quality and Fertility

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Aripiprazole, a third‐generation antidepressant/antipsychotic drug, acts on serotonergic and dopaminergic receptors and is widely prescribed for mental disorders, such as depression and schizophrenia. Studies indicate that this class of drugs can impact directly on sperm quality and fertility.
Maria Joana Nogueira de Moura   +7 more
wiley   +1 more source

Developing a Trauma Checklist for People With a Learning Disability Accessing Community Health and Support Services

open access: yesBritish Journal of Learning Disabilities, Volume 54, Issue 1, Page 74-84, March 2026.
ABSTRACT Background Research suggests people with a learning disability experience high prevalence of adverse life events which may result in trauma‐related mental health conditions. Identifying trauma‐related mental health conditions can facilitate access to support, however research suggests they may be under‐identified in this group. The aim of this
Sarah Wigham   +7 more
wiley   +1 more source

Association between glucagon‐like peptide‐1 receptor agonists and risk of dementia in older adults with type 2 diabetes: A target trial emulation

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1984-1996, March 2026.
Abstract Aim Type 2 diabetes (T2D) is associated with increased dementia risk, but comparative data across newer glucose‐lowering therapies remain limited. We examined whether the initiation of GLP‐1 receptor agonists (GLP‐1 RAs) was associated with incident dementia compared with DPP4 inhibitors (DPP4is) and SGLT2 inhibitors (SGLT2is) in older adults ...
Ting Zhou   +9 more
wiley   +1 more source

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