Results 191 to 200 of about 46,160 (296)

Comparative analysis of the characteristics and trends of adverse drug reaction reports from patients in Japan and the Japanese Adverse Drug Event Report database

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 515-524, February 2026.
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya, Ryohkan Funakoshi, Koichi Masuyama, Nariyasu Mano, Satoko Hori, Taku Obara   +5 more
wiley   +1 more source

Drug-Induced Parkinsonism: A Structured, Mechanism-Informed Approach to Identification and Management. [PDF]

Cureus
De Faria Sousa B, Espinosa JB.
europepmc   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

Priapism following antipsychotic-gabapentinoid combination in a case of treatment-resistant schizophrenia: a case report. [PDF]

BMC Psychiatry
Haque T, Shastri K, Naguib B, Ayre MJ.
europepmc   +1 more source

Olanzapine Overdose—Induced Bradycardia in a Young Adult With Major Depressive Disorder: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Olanzapine, an atypical antipsychotic widely used for psychiatric disorders, is typically associated with tachycardia and QT prolongation in overdose, while bradycardia remains a rare and underrecognized effect. We report a 20‐year‐old woman with major depressive disorder who presented 4 h after ingesting 100 mg of olanzapine in a suicide ...
Mohammad Ghasemi Palangi, Hassan Ahangar, Nona Sakhaie, Payman Yasami   +3 more
wiley   +1 more source

Adjunctive treatment with evenamide, a glutamate modulator, is associated with clinically meaningful benefits in patients with treatment-resistant schizophrenia and inadequate response to antipsychotics: recent clinical findings from randomized trials. [PDF]

Ther Adv Psychopharmacol
Anand R, Turolla A, Chinellato G, Sansi F, Roy A, Hartman R.   +5 more
europepmc   +1 more source

Anti‐NMDA Receptor Encephalitis Presenting as Acute Psychosis

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Young adults presenting with acute psychiatric symptoms followed by rapid neurological decline, catatonia, and autonomic instability should prompt consideration of anti–NMDA receptor encephalitis, even without detectable tumors; early recognition and immunotherapy are critical for favorable neurological recovery.
Tatiana Mengistu, Anuj Subedi, Uchenna Unamba, Sajjad Ahmed Khan, Esereoghene Mowoe, Jeremy Lane, Sahar Panah, Huma Kausar   +7 more
wiley   +1 more source

Rethinking Treatment-Resistant Depression: A Systematic Review of Novel Therapeutic Strategies and Precision Medicine Approaches. [PDF]

Actas Esp Psiquiatr
Tatlı SZ, Atagün Mİ.
europepmc   +1 more source

Double‐Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Antipsychotics can exert antibacterial effects via several mechanisms: (1, 2) Due to their amphiphilic and cationic characteristics, antipsychotics can negatively affect the integrity of the plasma membrane by disrupting its structure and electrochemical potential.
Navid Faraji, Mohammad Abavisani, Negar Ebadpour, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Comparison of droperidol and haloperidol for acute agitation in the emergency department: A retrospective cohort study. [PDF]

Ment Health Clin
DiGuglielmo F, D'Amico M, Martine J, Sastic C, Vuong T.   +4 more
europepmc   +1 more source