Results 11 to 20 of about 11,448 (254)

Simple spectrophotometric methods for the simultaneous determination of antipyrine and benzocaine

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2016
Antipyrine and benzocaine are formulated together for the treatment of ear inflammation and to relieve pain. Four spectrophotometric methods were developed for the simultaneous determination of antipyrine (AN) and benzocaine (BE) in their combined dosage
Hanan A. Merey
doaj   +1 more source

Synthesis of a new azo Schiff base colorimetric chemosensor for detection of cyanide and acetate anions [PDF]

open access: yesشیمی کاربردی روز
In this paper, a novel azo Schiff base chemosensor was synthesized via condensation reaction of 4-Aminoantipyrine with 1-(3-Formyl-4-hydroxyphenylazo)-3-nitrobenzene. The imine sensor was studied via spectroscopic methods IR, 1HNMR and UV-Vis.
Raziyeh Arabahmadi
doaj   +1 more source

Molecular Docking and Fluorescence Characterization of Benzothieno[3,2-d]pyrimidin-4-one Sulphonamide Thio-Derivatives, a Novel Class of Selective Cyclooxygenase-2 Inhibitors

open access: yesMolecules, 2014
The aims of this study were: (i) to explore the structure-activity relationship of some new anti-inflammatory benzothieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives 1–11; and (ii) to evaluate the possibility of using the most active compounds ...
Mariarita Barone   +5 more
doaj   +1 more source

Differential Metal Ion Sensing by an Antipyrine Derivative in Aqueous and β-Cyclodextrin Media: Selectivity Tuning by β-Cyclodextrin.

open access: yesAnalytical Chemistry, 2018
β-Cyclodextrin (β-CD) is a nontoxic cyclic oligosachcharide that can encapsulate all or part of organic molecules of appropriate size and specific shape through noncovalent interaction.
G. Selvan   +6 more
semanticscholar   +1 more source

Titanium nanoparticles (TiO2)/graphene oxide nanosheets (GO): an electrochemical sensing platform for the sensitive and simultaneous determination of benzocaine in the presence of antipyrine.

open access: yesIn Analysis, 2017
An effective electrochemical sensing platform for the simultaneous determination of benzocaine (BEN) and antipyrine (ANT) based upon titanium dioxide nanoparticle (TiO2)/graphene oxide nanosheet (GO) bulk modified carbon paste electrodes (TiO2-GO/CPE) is
Mona A. Mohamed   +5 more
semanticscholar   +1 more source

The impact of cocaine and heroin on the placental transfer of methadone

open access: yesReproductive Biology and Endocrinology, 2009
Background Methadone is the therapeutic agent of choice for the treatment of opiate addiction in pregnancy. The co-consumption (heroin, cocaine) which may influence the effects of methadone is frequent.
Wenzinger Silvana   +3 more
doaj   +1 more source

Why amphibians are more sensitive than mammals to xenobiotics. [PDF]

open access: yesPLoS ONE, 2009
Dramatic declines in amphibian populations have been described all over the world since the 1980s. The evidence that the sensitivity to environmental threats is greater in amphibians than in mammals has been generally linked to the observation that ...
Angelo Quaranta   +3 more
doaj   +1 more source

Administration Studies in Equine Antidoping Research: Designing Scientific Investigations to Effectively Direct Medication Control in Racehorses. [PDF]

open access: yesDrug Test Anal
ABSTRACT Pharmacokinetics is the study of the movement of drug in the body and includes the processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the pharmacologic effect of the drug on the body. The pharmacokinetics of a drug determines its pharmacologic effect. Pharmacokinetic studies describe drug concentrations while
Knych HK.
europepmc   +2 more sources

1,1′,5,5′-Tetramethyl-2,2′-diphenyl-4,4′-[p-phenylenebis(methylidynenitrilo)]di-1H-pyrazol-3(2H)-one

open access: yesActa Crystallographica Section E, 2008
In the centrosymmetric title compound, C30H28N6O2, the dihedral angles between the antipyrine ring and the terminal phenyl and central benzene rings are 50.55 (10) and 14.62 (9)°, respectively.
Yan Xiao   +6 more
doaj   +1 more source

Placental transfer and tissue accumulation of dolutegravir in the ex vivo human cotyledon perfusion model.

open access: yesPLoS ONE, 2019
ObjectiveTo determine the transplacental pharmacokinetics of the HIV integrase inhibitor dolutegravir.Study designMaternal-to-fetal transfer across the term human placenta was investigated with the ex-vivo dually perfused cotyledon model, in 5 closed ...
Laurent Mandelbrot   +5 more
doaj   +1 more source

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