As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley +1 more source
Se presentan los resultados del estudio realizado por el Grupo de Enfermedades Infecciosas de la Sociedad Española de Sanidad Penitenciaria (GEISESP) sobre la opinión de los facultativos penitenciarios en cuanto a la conveniencia o no de realizar el ...
P. Saiz De la Hoya +2 more
doaj
Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study. [PDF]
Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood.
Boulle, Andrew +13 more
core +7 more sources
Nur77 Is Associated With Polyfunctional Properties in Virus‐Specific Human CD8+ T Cells
Nur77 is associated with a TCF‐1+ memory‐like, polyfunctional profile in virus‐specific human CD8+ T cells across acute‐resolved, vaccinated, and chronic viral infections, and its pharmacologic modulation in vitro enhances the functionality of dysfunctional HIV‐ and HBV‐specific CD8+ T cells in chronic co‐infections. ABSTRACT Human CD8+ T cells undergo
Fabiola Martel +14 more
wiley +1 more source
Background Although highly active antiretroviral therapy (HAART) has improved HIV survival, some patients receiving therapy are still dying. This analysis was conducted to identify factors associated with increased risk of post-HAART mortality.
Lifson Alan R +10 more
doaj +1 more source
Assessment of the effect of a protein calorie supplement on change in CD4 count among art-naïve female TB patients co-infected with HIV in Dar Es Salaam, Tanzania [PDF]
RATIONALE: Tuberculosis and HIV infection together form a highly mortal combination. Even after the advent of highly active antiretroviral therapy (HAART) medications, management for Tuberculosis and HIV/AIDS still remains a challenge. Poor outcomes (in
Magohe, Albert Katana
core +1 more source
Reconstitution of hepatitis B virus (HBV)-specific T cell responses with treatment of human immunodeficiency virus/HBV coinfection [PDF]
Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus (HBV)-coinfected patients receiving highly active antiretroviral therapy (HAART).
Bertoletti, A +4 more
core +1 more source
Soft Tissue Sarcoma Burden and Research Productivity: Global Patterns and Disparities, 1990–2021
ABSTRACT Background Soft tissue sarcoma (STS) is a rare and diverse type of cancer, with a disproportionate incidence and limited global epidemiological studies. This study aims to analyze the long‐term trends and epidemiological features of the global burden of STS from 1990 to 2021 and to reveal the global research productivity on STS.
Hongjie Pan +8 more
wiley +1 more source
Dyslipidemia in AIDS patients on highly active antiretroviral therapy
Highly active antiretroviral therapy (HAART) reduces AIDS-related morbidity and mortality, however it has been associated with metabolic abnormalities. This study estimated the prevalence of lipid abnormalities and related factors among patients on HAART.
Max Weyler Nery +2 more
doaj +1 more source
Cost-effectiveness of a nurse-based intervention (AIMS) to improve adherence among HIV-infected patients : Design of a multi-centre randomised controlled trial [PDF]
Peer reviewedPublisher ...
de Bruin, Marijn +9 more
core +4 more sources

