Results 91 to 100 of about 8,379,610 (258)

Antiretroviral resistance in HIV-infected Saudi children failing first-line highly active antiretroviral therapy

Annals of Saudi Medicine, 2012
BACKGROUND AND OBJECTIVES: The use of a potent combination of antiretroviral (ARV) drugs, so-called highly active ARV therapy (HAART), has dramatically improved the quality of life and overall survival of children with human immunodeficiency virus (HIV ...
Sami Hussain Al Hajjar, Husn Frayha, Sahar Althawadi   +2 more
doaj   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

Bioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins, Adrian Carter, John Gardner   +2 more
wiley   +1 more source

Cost-effectiveness of highly active antiretroviral therapy in South Africa.

PLoS Medicine, 2006
BackgroundLittle information exists on the impact of highly active antiretroviral therapy (HAART) on health-care provision in South Africa despite increasing scale-up of access to HAART and gradual reduction in HAART prices.Methods and findingsUse and ...
Motasim Badri, Gary Maartens, Sundhiya Mandalia, Linda-Gail Bekker, John R Penrod, Robert W Platt, Robin Wood, Eduard J Beck   +7 more
doaj   +2 more sources

Social Representations of Aids and of the Antiretroviral Therapy for People Living with HIV

Psicologia, 2008
The aim of this study was to characterize the social representation of Aids and Highly Active Antiretroviral Therapy (HAART) for people living with HIV that have adherence to treatment, users of the public health services of Florianópolis, Santa Catarina.
Tatiana de Lucena Torres, Brígido Vizeu Camargo   +1 more
doaj  

Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study

Journal of Global Infectious Diseases, 2013
Background: Highly active antiretroviral therapy regimens have resulted in the systemic/clinical healing for human immune deficiency virus-infected patients but the consequence of antiretroviral therapy on the whole quality of life has become a major ...
Harminder Singh, Kamalpreet Kaur, Navin Dulhani, Akash Bansal, Bithika N Kumar, Vinod Kumar Singh Chouhan   +5 more
doaj   +1 more source

Monitoring of highly active antiretroviral therapy in HIV infection

Current Opinion in Infectious Diseases, 2011
Patients on antiretroviral therapy (ART) in high-income countries have routine laboratory tests to monitor ART efficacy/toxicity. We review studies describing the outcomes and costs of different monitoring approaches, predominantly in low-income countries.CD4 cell counts, HIV RNA viral load and clinical events are frequently discordant; viral load ...
Walker, A, Gibb, D
openaire   +3 more sources

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN RESIDUAL VIREMIA AND CHRONIC INFLAMMATION IN PATIENTS ON LONG-TERM ANTIRETROVIRAL THERAPY [PDF]

, 2013
Since the development of combination antiretroviral therapy, morbidity and mortality due to AIDS-related malignancies has declined significantly. In most patients, daily administration of a multidrug antiretroviral regimen is sufficient to suppress ...
Hilldorfer IV, Benedict B.
core  

Assessing the Efficacy of Highly Active Antiretroviral Therapy in the Brain

Brain Pathology, 2003
The devastating effects of HIV infection have been documented for the last 2 decades. Since the 1980s over 60 million people have been infected and at present 40 million people globally are living with HIV (72). HIV infects the central nervous system (CNS) early in the disease process.
Kandanearatchi, A, Williams, B P, Everall, I P   +2 more
openaire   +4 more sources

Associations between prior wasting malnutrition and indices of insulin secretion and sensitivity among six cohorts from Asia and Africa: The SAMPA study

Diabetic Medicine, EarlyView.
Abstract Aims The role of prior wasting malnutrition (PM) in determining insulin sensitivity and secretion in low‐ and middle‐income countries (LMICs) remains unclear. We investigated associations of insulin indices with PM and whether these were modified by current body mass index (BMI).
Sharon E. Cox, Sana Ahmed, Dixi Paglinawan Modoc, Riddhi Dasgupta, Christina Christoffersen, Molly Chisenga, Julius Patrick Ferrer, Ruth Frikke‐Schmidt, Rikke Krogh‐Madsen, Belinda Kweka, Nanette Lee, Evangelista Malindisa, Mizinga J. Tembo, Patrick Ngoya, Dorothea Nitsch, Daniel Faurholt‐Jepsen, George PrayGod, Geeta Trilok‐Kumar, Suzanne Filteau, James A. M. Shaw   +19 more
wiley   +1 more source