Results 91 to 100 of about 46,100 (197)

HIV Infection and Opioid Treatment Enable the Engraftment of Kaposi Sarcoma‐Like Tumors Into Immunocompetent Mice

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT The Kaposi Sarcoma herpesvirus (KSHV) causes Kaposi sarcoma (KS), primary effusion lymphoma, a lymphoproliferative disease (KSHV‐multicentric Castleman's disease), and a cytokine inflammatory syndrome (KICS). These diseases occur more frequently, though not exclusively, among people living with HIV or other types of immune dysregulation. While
Julian Naipauer, Ezequiel Lacunza, Anuj Ahuja, Santas Rosario, Carolina Alejandra Alvarez Canete, Martin C. Abba, Ethel Cesarman, Sundaram Ramakrishnan, Enrique Mesri, Sabita Roy, Umakant Sharma   +10 more
wiley   +1 more source

sVCAM‐1 and Hematological Profiles Are Associated With CD4‐Defined Disease Status in HIV Infection

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Brazil stands out for its progressive public health policies against HIV, including universal access to antiretroviral therapy and a stricter AIDS definition (CD4 < 350 cells/mm3) compared to the World Health Organization (WHO) criterion (CD4 ≤ 200 cells/mm3).
Bruno Almeida‐Silva, Claudeir Dias da Silva‐Junior, Victor Vaitkevicius‐Antão, Melayne Rocha Aciole, Milena Márcia da Silva, Líbia Cristina Rocha Vilela Moura, Paulo Sergio Ramos de Araujo, Michelle Christiane da Silva Rabello, Virginia Maria Barros de Lorena   +8 more
wiley   +1 more source

CD8+ Tissue‐Resident Memory T Cells in Health and Disease

MedComm, Volume 7, Issue 7, July 2026.
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai, Ting‐Ting Xu, Sen Lin, Meng‐Yu Xiao, Yun‐Xia Lin, Hao‐Wen Ma, Yue‐Yang Liu, Yao‐Jie Wang, Lu‐Ning Yin, Mei Huang, Yong‐Da Liu, Chao Zhu, Xiao‐Ting Zhu, Ji‐Hang Yuan   +13 more
wiley   +1 more source

The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity

MedComm, Volume 7, Issue 7, July 2026.
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng, Qilong Li, Ning Jiang, Qijun Chen   +3 more
wiley   +1 more source

Trends in Pharmacist‐Prescribed Dispensing Records of HIV Pre‐Exposure (2020–2025) and Post‐Exposure Prophylaxis (2020–2024) in Brazil: A Time Series Analysis

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 7, July 2026.
ABSTRACT Purpose Pharmacist prescribing of HIV pre‐exposure (PrEP) and post‐exposure prophylaxis (PEP) is an emerging strategy to expand access to HIV prevention, but real‐world evidence on its implementation remains limited. We assessed national and regional trends in pharmacist‐prescribed dispensing records of PrEP (2020–2025) and PEP (2020–2024) in ...
Gustavo Magno Baldin Tiguman, Dyego Carlos Souza Anacleto de Araújo, Patricia Melo Aguiar   +2 more
wiley   +1 more source

Dysregulated Metabolism in People Living With HIV in the Modern ART‐Era: A Systematic Review of Targeted Metabolomics Studies

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia, Du Toit Loots, Shayne Mason, Esme Jansen Van Vuren, Monray E. Williams   +4 more
wiley   +1 more source

HIV Transmission and Immunology of the Male Reproductive Tract

American Journal of Reproductive Immunology, Volume 96, Issue 1, July 2026.
ABSTRACT The penile epithelium, encompassing multiple anatomical sites, is the primary location of human immunodeficiency virus (HIV) acquisition in heterosexual men. Although the per‐contact risk of penile HIV acquisition is generally low, substantial global discrepancies in HIV prevalence still exist, particularly in low‐income regions.
Jinny Tsang, Rachel Liu, Rameen Jamil, Ronald Moses Galiwango, Brenda Okech, Sanja Huibner, Marcio Gabriel A. de Carvalho, Lane B. Buchanan, Cindy M. Liu, Aaron A. R. Tobian, Jessica L. Prodger, Rupert Kaul   +11 more
wiley   +1 more source

The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies

American Journal of Reproductive Immunology, Volume 96, Issue 1, July 2026.
ABSTRACT Sex hormones and reproductive transitions profoundly shape immune, metabolic, neuropsychological, and mucosal biology, as well as HIV persistence, across women's lives. Although women constitute the majority of people with HIV worldwide, hormonal and reproductive biology are still not sufficiently incorporated into HIV cure research. Cisgender
Elizabeth Hastie, Priya Khetan, Sarah A. LaMere, Ashley F. George, Rebecca Abelman, Kathleen Weber, Phyllis C. Tien, Judith D. Auerbach, Maile Karris, Todd Brown, Jonathan Karn, Loreen Willenberg, Dawn Averitt, Bridgette Picou, Nadia R. Roan, Eileen P. Scully, Karine Dubé, Nancie Archin, Sara Gianella   +18 more
wiley   +1 more source

The Future of the HIV Response: Sustaining Progress in an era of Political Uncertainty and Scientific Opportunity

American Journal of Reproductive Immunology, Volume 96, Issue 1, July 2026.
ABSTRACT The global HIV response is at a pivotal juncture. The field is experiencing a paradox: rapid scientific innovation alongside increasing fragility in financing, political commitment, and implementation systems. Significant progress has been made in expanding access to HIV treatment and prevention, but major gaps in coverage and equity existed ...
Mitchell Warren
wiley   +1 more source

Perceptions of Buprenorphine With Naloxone Treatment and the Fear of Precipitated Withdrawal: A Qualitative Exploration With HIV Prevention Trials Network 094 INTEGRA Participants and Staff

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Uptake of evidence‐based medication for opioid use disorder (MOUD), including buprenorphine–naloxone, remains low despite the expanding US opioid crisis. This study examined participants' and staff perceptions of adopting and delivering buprenorphine–naloxone on a mobile unit providing integrated MOUD and HIV services for people ...
Rose A. Schmidt, Amaya Perez‐Brumer, Peter Davidson, Steve Shoptaw, Nabila El‐Bassel, Philip Andrew, Jayla Harris, Omar Nieto, Sydney Bornstein, Rashaunna Redd, Jessica Yeager, David Goodman‐Meza, Albert L. Hasson, Marc Seigel, Cecile Denis, Renee El‐Krab, Laramie R. Smith, on behalf of the HPTN 094 Team   +17 more
wiley   +1 more source